Pyogenic granuloma is a relatively common benign lesion of the skin and/or mucosal surfaces, accounting for 0.5% of all skin nodules in children in the United States alone (Lin et al, 2004). The aetiology is still poorly understood but trauma, hormonal influence, viral oncogenes, microscopic arteriovenous malformations and growth factors (e.g. tumour angiogenesis factor – Patrice et al, 1991) h...

Pyogenic granulomas are common, acquired, benign vascular lesions of the skin and mucous membranes that can develop both spontaneously and traumatically. We present a unique case of a four-year healthy, uncircumcised boy with multiple pyogenic granuloma on the mucous face of the penis foreskin. Although penile multiple pyogenic granulomas have previously been described in adults, there are no r...

A pyogenic granuloma (PG) is a rapidly growing benign vascular tumor that can be found on the skin or subcutaneous tissue. While some pyogenic granulomas may resolve spontaneously, most have a tendency to bleed easily and require treatment. Current therapeutic modalities include topical imiquimod, cryotherapy, electrodessication, curettage, excision, laser therapy, sclerotherapy, and microembol...

Pyogenic granuloma is thought to represent an exuberant tissue response to local irritation or trauma. It is a tissue reactional to constant minor trauma and might be related to hormonal changes. Clinically these lesions usually present as single nodule or sessile papule with smooth or lobulated surface. The size at diagnosis may vary from a few millimeters to several centimeters. Pyogenic gran...

Pyogenic Granuloma are benign vascular lesions that occur most commonly on the acral skin and on the oral mucous membrane of children and young adults. The term pyogenic granuloma is a misnomer since it does not produce any purulent secretion, not related to any infection and does not even represent a granuloma histologically. Clinically it appears as pink to red coloured smooth or lobulated ex...

INTRODUCTION Only ten cases of primary pyogenic spondylitis following vertebroplasty have been reported in the literature. To the best of our knowledge, we present the first reported case of primary pyogenic spondylitis and spondylodiscitis caused by kyphoplasty. CASE PRESENTATION A 72-year old Caucasian man with an osteoporotic compression fracture of the first lumbar vertebra after kyphopla...

Identifying the causative pathogens in patients with pyogenic vertebral osteomyelitis is important for optimizing antibiotic therapy. Thus, we examined patient characteristics and investigated the efficacy of the combined use of blood culture and image-guided biopsy culture for identifying the causative pathogens of pyogenic vertebral osteomyelitis. A case series study was conducted in hospital...

Cutaneous toxicities under therapy with selective BRAF inhibitors such as vemurafenib or encorafenib (LGX818) are frequent, including plantar hyperkeratosis, squamous cell carcinoma, and second primary melanoma. Pyogenic granuloma is a benign, rapidly growing, eruptive hemangioma that often bleeds and ulcerates. Common causes are mechanical trauma and cast immobilization, as well as multiple dr...

BACKGROUND Patients with liver cirrhosis are at increased risk of serious bacterial infections carrying a high case fatality rate. Case reports have suggested an association between liver cirrhosis and pyogenic liver abscess. AIMS To estimate the risk and case fatality rate of pyogenic liver abscess in Danish patients with liver cirrhosis compared with the background population. METHODS Ide...

Pyogenic granuloma is a benign vascular tumor that may affect the gastrointestinal tract. This report describes a rare case of sigmoid-colon pyogenic granuloma in a 4-month-old boy causing intussusception. Resection and anastomosis were curative. The mother had history of high dose of progesterone exposure during initial weeks of conception for vaginal bleeding. This may point towards etiology ...