We describe a 3 year old girl with the typical clinical features of the X linked recessive condition, Hunter's disease. The diagnosis was confirmed by the pattern of urinary excretion of glycosaminoglycans and the absence of iduronate sulphatase activity in her fibroblasts. She also had an apparently balanced reciprocal chromosomal translocation 46XX,t(X:5) with the X breakpoint being between q...

Sex-determining region Y-box protein 2 (SOX2) is an embryo transcription factor located on chromosome 3q26.3-q27. It plays an important role in the maintenance of differentiation and self-renewal of pluripotent stem cells. Studies have shown that SOX2 is associated with multiple cancers and is overexpressed in many different phenotypes of breast cancer. To study the relationship between SOX2 an...

in the sample population ranged from 31% to 92% (mean 68%). Two regions of the chromosome arm showed Al values greater than the background range of 10-22% (mean 17%) of informative cases that was observed with five markers spanning 6q21 -q25.2. Firstly, seven markers gave Al values that averaged 35% in a region flanked by D6S313 (Al = 10%) at 6ql3 and D6S283 (Al = 17%) at 6qI6.3-21. The second ...

Chromosome analysis using conventional staining, G banding, and, after BUdR incorporation, two R banding methods, one using Hoechst and one acridine orange, were performed on lymphocytes from a pair of female monozygotic twins. The culture conditions were designed to show the presence of the fragile X (q27-28) which had previously been found to be segregating in the family. One twin was of high...

During the 2014-2017 period, wheat samples were collected from discoloured spikes affected by Fusarium head blight (FHB) 20 locations in Serbia. After isolation, fungi cultivated on potato dextrose agar (PDA) at 25oC for 7 days. Based situ identification PDA, 36 isolates of section Liseola selected further analyses. The pathogenicity all was confirmed leaves. virulence determined measuring leng...