F(2) populations are commonly used in genetic studies of animals and plants. For simplicity, most quantitative trait locus or loci (QTL) mapping methods have been developed on the basis of populations having two distinct genotypes at each polymorphic marker or gene locus. In this study, we demonstrate that dominance can cause the interactions between markers and propose an inclusive linear mode...

BACKGROUND Dense marker maps require efficient statistical methods for QTL fine mapping that work fast and efficiently with a large number of markers. In this study, the simulated dataset for the XIIth QTLMAS workshop was analyzed using a QTL fine mapping set of tools. METHODS The QTL fine-mapping strategy was based on the use of statistical methods combining linkage and linkage disequilibriu...

SUMMARY R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by ...

In Arabidopsis recombinant inbred line (RIL) populations are widely used for quantitative trait locus (QTL) analyses. However, mapping analyses with this type of population can be limited because of the masking effects of major QTL and epistatic interactions of multiple QTL. An alternative type of immortal experimental population commonly used in plant species are sets of introgression lines. H...

Identifying natural allelic variation that underlies quantitative trait variation remains a fundamental problem in genetics. Most studies have employed either simple synthetic populations with restricted allelic variation or performed association mapping on a sample of naturally occurring haplotypes. Both of these approaches have some limitations, therefore alternative resources for the genetic...

The cucumber (Cucumis sativus L.) exhibits extensive variations in fruit size and shape. Fruit length is an important agronomic and domesticated trait controlled by quantitative trait loci (QTLs). Nonetheless, the underlying molecular and genetic mechanisms that determine cucumber fruit length remain unclear. QTL-seq is an efficient strategy for QTL identification that takes advantage of bulked...

Northern Corn Leaf Blight (NCLB) is a foliar disease, caused by fungal pathogen (Setosphaeria turcica) that damages maize crop due to heavy losses in every year. A study was conducted for NCLB and identified quantitative trait loci (QTLs) maize. Mapping population F2:3 families developed involving two inbreds viz CM 212 (susceptible) & 145 (resistant).The mapping evaluated environments (BHU...

Quantitative trait loci (QTL) were mapped in the woody perennial Douglas fir (Pseudotsuga menziesii var. menziesii [Mirb.] Franco) for complex traits controlling the timing of growth initiation and growth cessation. QTL were estimated under controlled environmental conditions to identify QTL interactions with photoperiod, moisture stress, winter chilling, and spring temperatures. A three-genera...

the availability of the saturated dna marker maps in livestock has made it possible to locate quantitative trait loci (qtl) in these domestic animals. the objective of this research was to investigate the principles of applying the simple regression for qtl analysis in paternal half-sib (phs) design commonly used in livestock species. the theoretical aspects of the simple regression approach fo...

The objective of this study was to identify the quantitative trait loci (QTL) affecting carcass traits on chromosome 1 in Japanese quail. The populations comprised of 422 progeny in 9 half-sib families. Phenotypic data on carcass weight, carcass parts, and the internal organs were collected on 422 progeny. Nine half-sib families were genotyped for 8 microsatellite markers covering chromosomes 1...