We have studied the structural and viscoelastic properties of assembling networks of the extracellular matrix protein type-I collagen by means of phase contrast microscopy and rotating disk rheometry. The initial stage of the assembly is a nucleation process of collagen monomers associating to randomly distributed branched clusters with extensions of several microns. Eventually a sol-gel transi...

33 Spaceflight has profound effects on vascular function as a result of weightlessness that 34 may be further compounded by radiation exposure. The purpose of the present study was 35 to assess the individual and combined effects of hindlimb unloading (HU) and radiation 36 (Rad) on vasodilator responses in the skeletal muscle vasculature. Adult male C57BL/6J 37 mice were randomized to one of fo...

Rad is the prototypic member of a family of novel Ras-related GTPases that is normally expressed in heart, skeletal muscle, and lung and that has been shown to exhibit a novel form of bi-directional interaction with the nm23 metastasis suppressor. In the present study, we have investigated the expression of Rad in normal and neoplastic breast tissues by Western blot and immunohistochemistry and...

Ab initio and density functional calculations predict that intramolecular homolytic substitution reactions of oxyacyl radicals at the selenium atom in ω-alkylseleno-substituted radicals proceed via mechanisms that do not involve hypervalent intermediates. When the leaving radical is tert-butyl, energy barriers ("G‡) for these reactions range from 27.1 (G3(MP2)RAD) kJ mol−1 for the formation of ...

Wrist and elbow angular kinematics and racket acceleration at impact were measured in the tennis one-handed back-hand drive for three groups of players: Professionals with no history of tennis elbow (PRO), intermediates with no history of tennis elbow (- TE), and intermediates with a history of tennis elbow (+ TE). Electrogoniometer, strain gauge, and accelerometer signals were sampled for thir...

Fish exhibit impressive locomotive performance and agility in complex underwater environments, using their undulating tails pectoral fins for propulsion maneuverability. Replicating these abilities robotic fish is challenging; existing designs focus on either fast swimming or directional control at limited speeds, mainly within a confined environment. To address limitations, we designed Snapp, ...

The repeating fast radio burst source FRB 121102 has been shown to have an exceptionally high and variable Faraday rotation measure (RM), which must be imparted within its host galaxy likely by or local environment. In the redshifted ($z=0.193$) reference frame, RM decreased from $1.46\times10^5$~rad~m$^{-2}$ $1.33\times10^5$~rad~m$^{-2}$ between January August 2017, showing day-timescale varia...