The development of a radiation-induced sarcoma (RIS) in the post mastectomy thoracic treatment volume is an infrequent, but recognized, event. Its frequency is rising in relation with increasing survival of breast cancer patients treated with adjuvant radiation therapy, and is associated with poor prognosis despite treatment. We present a case of leiomyosarcoma in a patient who underwent mastec...

Radiation-refractory and progressive Kaposi's sarcoma remains a challenge for the oncologist. Systemic chemotherapy has improved, but results are poor. Gemcitabine is largely employed in oncology for its high therapeutic rates. We report four cases of patients with radiation-refractory and progressive classic Kaposi's sarcoma, two of whom were pre-treated with chemotherapy and then underwent tr...

background: ionizing radiation causes deleterious effects on living system mainly due to oxidative damages of macromolecules and protein is the major target due to its abundance. the aim of this study was to investigate the effects of ionizing radiation induced changes in the molecular properties of bovine serum albumin (bsa) its secondary and tertiary structures, degradation, cross linking and...

Introduction: Post-irradiation mammary stromal sarcoma (MSS) is a rare condition, and it worth learning new knowledge from each case. Case Presentation: We present the case report of 59-year-old female with medical history breast cancer, who presented an axillary mass on same side. The patient was further evaluated finally diagnosed MSS chondroid differentiation. Thereafter, she underwent neoad...

We describe a pediatric patient with histiocytic sarcoma involving the T6 and L4 vertebral bodies and the lungs. His tumor progressed during chemotherapy designed for Langerhans' cell histiocytosis and sarcoma. High-dose radiation, on the other hand, was effective.

Most cases of Ewing's sarcoma are reported in the bone, and extraosseous Ewing's sarcoma is an extremely rare disease. Here, we report a rare case of primary pulmonary Ewing's sarcoma in a patient with hemoptysis. The patient underwent right upper lung lobe lobectomy with adjuvant chemotherapy and radiation therapy and has been free of recurrent disease for 4 years.

60 Comparison of Effects of Daily versus Hyperfractionated Split-Course Radiation Schedules with and with out Cyclophosphamide on Median Survival, Meta static Dissemination, Tumor Cure, and Growth Rates. William B. Looney, Harold A. Hopkins, Mark B. Longerbeam, and Walter H. Carter, Jr. 68 Action of Retinoids on the Anchorage-independent Growth of Normal Rat Kidney Fibroblasts Induced by 12-O-T...

BACKGROUND γ-radiation is an effective treatment for cancer. There is evidence that radiotherapy supports tumor-specific immunity. It was described that irradiation induces de novo protein synthesis and enhances antigen presentation, we therefore investigated whether γ-radiation results in increased expression of cancer-testis (CT) antigens and MHC-I, thus allowing efficient immunological contr...