Thyroxine, if not truly the active thyroid hormone ( 1, 2) is clearly the principal iodine-containing compound released by the thyroid gland, and ordinarily comprises the largest fraction of the plasma's protein-bound iodine (3-6). Many investigators have, therefore, attempted to assess thyroidal function by measuring the concentration of protein-bound I'll (PB1181) in the plasma following the ...

IN THE euthyroid patient, rapid supraventricular tachyeardias occur and are often resistant to prophylactic treatment with quinidine or pronestyl.' In an attempt to evaluate the effect of radioactive iodine in cases of supraventricular tachycardia resistant to antiarrhythmnic drugs, the authors treated 25 such patients with radioactive iodine and observed them for periods up to 6 years.2 In all...

IN THE euthyroid patient, rapid supraventricular tachyeardias occur and are often resistant to prophylactic treatment with quinidine or pronestyl.' In an attempt to evaluate the effect of radioactive iodine in cases of supraventricular tachycardia resistant to antiarrhythmnic drugs, the authors treated 25 such patients with radioactive iodine and observed them for periods up to 6 years.2 In all...

According to Harington, two fractions, one “thyroxine-like” and the other “diiodotyrosine-like,” can account for all of the organic iodine found in the thyroid gland (1). The metabolism of these compounds has been reviewed recently by Salter (2). The labeling of iodine by radioactivity provides for the first time a desirable tool for the study of the endogenous or normal rates of formation of t...

The early discovery that physiological activity’in the thyroid gland was associated with an iodoprotein (1, 2) led logically to investigations of the physiological effects and chemical properties of various proteins or protein fractions that had been subjected to artificial iodination. In 193334, Abelin et al. observed physiological effects resembling those produced by the thyroid gland after t...

PURPOSE This retrospective study was aimed at revealing the safety and short-term outcome of radioiodine treatment in patients with Graves' disease at outpatient clinic. METHODS From July 1999 to April 2002, 511 patients with Graves' disease were treated with radioiodine at the outpatient clinic of Tajiri Thyroid Clinic, Kumamoto. Of them, 73 patients dropped out or were referred to another m...

Graves' disease is a thyroid-specific autoimmune disorder in which the body makes antibodies to the thyroid-stimulating hormone receptor leading to hyperthyroidism. Therapeutic options for the treatment of Graves' disease include medication, radioactive iodine ablation, and surgery. Radioactive iodine is absolutely contraindicated in pregnancy as exposure to I-131 to the fetal thyroid can resul...

Hyperthyroidism is now recognized as the most common endocrinopathy of older cats. Despite worldwide occurrence, the pathogenesis of feline hyperthyroidism remains unclear. Traditional methods of managing feline hyperthyroidism include thyroidectomy, anti-thyroid medications, and radioactive iodine. Surgery and radioactive iodine are designed to provide permanent solutions, oral anti-thyroid dr...

BACKGROUND Recurrent papillary thyroid carcinoma (PTC) beyond the first two decades of definitive treatment (i.e. total thyroidectomy and radioactive iodine ablation) is a rare occurrence. CASE PRESENTATION We present a case of a 71-year old Caucasian female with a distant history of PTC treated with total thyroidectomy and radioactive iodine ablation who experienced recurrence of her disease...