OBJECTIVE The objective of this study was to investigate quality of life (QoL) in patients with Graves' disease treated with radioiodine or antithyroid drugs. DESIGN AND METHODS The design of the study consists of an open, prospective, randomized multicenter trial between radioiodine and medical treatment. A total of 308 patients were included in the study group: 145 patients in the medical g...

College of Physician’s guidelines on the use of radioactive iodine in hyperthyroidism. The original guidelines, produced in 1995 by a College Working Party, represented the bodies involved in the administration of radioiodine (131I).1 The need for these guidelines emerged from the outcome of a survey, reported in this Journal, which showed considerable variation within the UK in the doses of ra...

UNLABELLED Graves's disease is the most common cause of hyperthyroidism. There are three current therapeutic options: anti-thyroid medication, surgery, and radioactive iodine (I 131). There are few data in the literature regarding the effects of radioiodine therapy on the larynx and voice. The aim and the AIM os this study was: to assess the effect of radioiodine therapy on the voice of Based...

UNLABELLED Salivary gland dysfunction has been described in patients undergoing radioiodine therapy but associated lacrimal gland dysfunction (sicca syndrome) has never been reported. We conducted a prospective cohort study with follow-up for up to 3 y in a tertiary care university center to determine the prevalence of sicca syndrome in patients after high-dose radioiodine treatment. METHODS ...

RATIONALE Since ovarian function is only temporarily compromised by radioiodine therapy, many women with thyroid cancer treated with radioiodine can become pregnant. The present study evaluated the evolution of these pregnancies and the consequences for the offspring. PATIENTS AND METHODS We retrospectively analyzed 78 pregnancies of 66 women submitted to total thyroidectomy, followed by radi...

The effects of low-activity versus high-activity radioiodine regimens in thyroid remnant ablation for patients with differentiated thyroid carcinoma (DTC) under recombinant human thyrotropin (rhTSH) stimulation have been widely quoted but there has been no systematic review of the evidence. We undertook a systematic review of randomized controlled trials to assess the effects of low-activity ra...

Patterns of fecal radioiodine excretion were studied in seven normal young men with intact, unblocked thyroid glands, who received repeated oral daily doses of [125I]iodide in an attempt to achieve isotopic equilibrium. Fecal radioactivity was assumed to have originated either in the circulating inorganic radioiodine (radioiodide) compartment or in the circulating hormonal protein-bound iodine ...

OBJECTIVES/HYPOTHESIS The purpose of this study is to review our experience with sialendoscopy for the management of radioiodine-induced sialadenitis. METHODS Retrospective chart review of all patients with radioiodine-induced sialadenitis treated with interventional sialendoscopy. RESULTS Twelve female patients with a mean age of 46.5 years (range, 25-77 years) underwent interventional sia...

this is a retrospective study on clinical course and treatment response of patients with thyroid hot nodule, referred to nuclear medicine department of shariati hospital from 1360 to 1377. from the total 58 patients with average age of 43 yr and incidence peak of 40 yr, 81% were female and 19% were male. 64% of the patients were thyrotoxic and 36% were euthyroid at presentation. thyrotoxic symp...