نتایج جستجو برای: radioresistant

تعداد نتایج: 1156  

Journal: :Proceedings of the National Academy of Sciences 1985

2014
JUHO SUOJANEN ESA FÄRKKILÄ TESSA HELKAMAA VENLA LOIMU JYRKI TÖRNWALL CHRISTIAN LINDQVIST JAANA HAGSTRÖM KARRI MESIMÄKI

Renal cell carcinomas (RCCs) have a tendency to metastasize at an early stage, therefore, the patients frequently exhibit metastatic disease at the time of diagnosis. Common locations for the metastases are adjacent organs and abdominal lymph nodes; however, occasionally metastasis to the peripheral organs may be the initial clinical symptom. The 71-year-old male patient in the current case suf...

2014
Peijing Zhang Li Wang Cristian Rodriguez-Aguayo Yuan Yuan Bisrat G. Debeb Dahu Chen Yutong Sun M. James You Yongqing Liu Douglas C. Dean Wendy A. Woodward Han Liang Xianbin Yang Gabriel Lopez-Berestein Anil K. Sood Ye Hu K. Kian Ang Junjie Chen Li Ma

Tumour cells associated with therapy resistance (radioresistance and drug resistance) are likely to give rise to local recurrence and distant metastatic relapse. Recent studies revealed microRNA (miRNA)-mediated regulation of metastasis and epithelial-mesenchymal transition; however, whether specific miRNAs regulate tumour radioresistance and can be exploited as radiosensitizing agents remains ...

2017
Zhijie Xu Yuanliang Yan Lingfang Xiao Shuang Dai Shuangshuang Zeng Long Qian Lin Wang Xue Yang Yi Xiao Zhicheng Gong

Radiotherapy is a powerful tool in the treatment of cancer that has the advantage of preserving normal tissues. However, tumor radioresistance currently remains a major impediment to effective RT. Thus, exploring effective radiation sensitizers is urgently needed. In this study, we have shown that diosmetin, the aglycone of the lavonoid glycoside from olive leaves, citrus fruits and some medici...

Journal: :Cancer research 2001
J McIlrath S D Bouffler E Samper A Cuthbert A Wojcik I Szumiel P E Bryant A C Riches A Thompson M A Blasco R F Newbold P Slijepcevic

Telomere lengths in radiosensitive murine lymphoma cells L5178Y-S and parental radioresistant L5178Y cells were measured by quantitative fluorescence in situ hybridization. Results revealed a 7-fold reduction in telomere length in radiosensitive cells (7 kb) in comparison with radioresistant cells (48 kb). Therefore, it was reasoned that telomere length might be used as a marker for chromosomal...

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