Preaxial polydactyly is the most common duplication pattern in white and Asian populations (1). It is a congenital anomaly with a wide range of manifestations .Current classification do not have the capacity to classify all different types of radial polydactyly. We describe here a very rare and unusual case of bilateral preaxial polydactyly (triplication) in a woman and report the operations re...

California is home to many large government reservations that have been in existence for decades. Many of these reservations were formed to support various Department of Defense and Department of Energy national defense activities. Often, only a very small percentage of the reservation is actively used for programmatic activities, resulting in large areas of intact habitat. In some cases, this ...

the human leukocyte antigen has become a key component in investigating the genetic relationships between populations. the aim of this study was to determine the genetic diversity of hla class i and ii alleles among zaboli ethnic group of south-east iran to establish a database for further investigations on ancestry and the genetic factors contributing to complex diseases in this region. unrela...

Although human bitter taste perception is hypothesized to be a dietary adaptation, little is known about genetic signatures of selection and patterns of bitter taste perception variability in ethnically diverse populations with different diets, particularly from Africa. To better understand the genetic basis and evolutionary history of bitter taste sensitivity, we sequenced a 2,975 bp region en...

es, have a very low incidence and include diseases that occur at a prevalence of less than 5 cases per 10 000 people in the overall population (1). New rare diseases are discovered every year, and some of today’s known diseases in this category have patient populations of fewer than a hundred (2). In a country like Croatia (population of 4.5 million), most physicians do not see a single patient...

Congenital intracranial pial arteriovenous fistulas (AVFs) are rare cerebrovascular lesions. Their clinical manifestations tend to vary according to age, with pediatric populations being more likely to have symptoms like congestive cardiac failure and seizures because of arteriovenous shunting; hemorrhage is the major presentation in adult populations. Pediatric populations, especially newborn ...

There is rising interest in applying single-cell transcriptome analysis and other single-cell sequencing methods to resolve differences between cells. Pooled processing of thousands of single cells is now routinely practiced by introducing cell-specific DNA barcodes early in cell processing protocols ​. However, researchers must sequence a large number of cells to sample rare subpopulations ...