it has been hypothesized that elevated plasma homocysteine (hcy) plays a role in the pathogenesis of alzheimer’s disease (ad) and age-related cognitive decline. the mechanism of hcy neurotoxicity in the brain is controversial as well hcy is a ligand of nmda receptor. memantine, an uncompetitive antagonist of n-methyl-d-aspartate (nmda) receptors approved for the treatment of moderate to severe ...

One of the aging hypotheses is based on fact that percentage water in human body decreases with age. To a greater extent, loss affects most energy-dependent organs, such as liver, which undergoes number structural compensatory-adaptive changes. The parameters age-related changes are currently understudied. However, they should be taken into account when determining actual organ transformations ...

A spontaneous rhabdomyosarcoma was observed in a female Sprague Dawley-derived rat at 8 weeks of age. Histopathological examination when the rat was killed at 5 months of age revealed marked differences from experimentally-induced tumours.

The bandwidth-intensive applications on Smart-Mobile-Devices (SMDs) are increasing with SMD's colossal growth. overlapped cellular and non-cellular networks, in hot-spot-places, SMDs capabilities significant reasons for this interfaces-RAT (Radio-Access-Technology) can have complementary link characteristics. end-users avail always-best-connectivity (ABC) their RAT This paper proposes an Integr...