Sera from approximately two-thirds of patients with rheumatoid arthritis contain an antibody which is reactive with a nuclear antigen present in human B-lymphocyte tissue culture cells. The immunological reaction can be demonstrated by precipitation and immunofluorescence. Evidence is present that the reactive nuclear antigen is associated with Epstein-Barr (EB) virus-transformed lymphocytes. N...

Cytidine deaminase activity, C reactive protein, histidine, and erythrocyte sedimentation rate were measured in 36 subjects with psoriatic arthritis of varying disease duration and severity. Although cytidine deaminase activity may provide an integrated measure of synovial inflammation in rheumatoid arthritis, neutrophil accumulation in psoriatic plaques compromises this measure in psoriatic ar...

Microbes reach the synovial cavity either directly during bacteraemia or by transport within lymphoid cells or monocytes. This may stimulate the immune system excessively, triggering arthritis. Some forms of ReA correspond to slow infectious arthritis due to the persistence of microbes and some to an infection triggered arthritis linked to an extra-articular site of infection.

S higella infection is the least common of the gastroenteritis-inducing organisms which are associated with reactive arthritis (ReA) in developed countries, reflecting the scarcity of the organism in these environments. A recent thorough survey of Shigella infected subjects in Finland describes an annual incidence of Shigella induced ReA of only 1.3 per million. This compares with the incidence...

Arthritis is one of the common diseases. in this present study twenty patients with symptoms of arthritis were included is as control another twenty patients without arthritis are included. The serum samples of these patients were collected and left for RF(or) RA which detects the immunoglobulin of the class IgM, IgA and IgE and careful prognostic marker of RA ie IgM is detected. Different reag...

INTRODUCTION Acute Rheumatic Fever and Post Streptococcal Reactive Arthritis in adults can present in a similar manner. CASE PRESENTATION A 25 year old Caucasian male developed a transient crippling polyarthritis one month following treatment of a sore throat. The patient was found to meet criteria for both Acute Rheumatic Fever and Post Streptococcal Reactive Arthritis, leading to the questi...

BACKGROUND Distinguishing septic arthritis from transient synovitis of the hip in children can be challenging. Authors of recent retrospective studies have used presenting factors to establish algorithms for predicting septic arthritis of the hip in children. This study differs from previous work in three ways: data were collected prospectively, C-reactive protein levels were recorded, and the ...

A 57-year-old woman with rheumatoid arthritis (RA) and limited systemic sclerosis (lSSc) was suspected to have lymphadenopathy and primary biliary cirrhosis (PBC). Lymph node biopsy showed reactive follicular lymphadenopathy with intrafollicular plasmacyte infiltration that was interleukin-6 positive by immunohistostaining. Because of gradually worsening arthritis, tocilizumab was administered ...