37% (57/155) of sera from patients with rheumatoid arthritis contain cold-reacting lymphocytotoxic antibodies. Lymphocytotoxins were predominantly of the weakly reactive type and were more likely to be present in patients who were HLA-DR4 positive. By contrast, patients who were HLA-DR3 positive were more likely to have strongly reactive lymphocytotoxins. The lymphocyte subclass reactivity of t...

This literature review is aimed at exploring the significance of laboratory parameters in follow-up coronavirus disease-19, which latest global biohazard for humanity. Laboratory were classified under three main headings. These headings hematological tests, inflammatory and coagulation parameters. It has been determined that low lymphocyte count, one a condition seen every stage disease. High n...

Aim: Hashimoto's thyroiditis (HT) is a chronic autoimmune-mediated disease that leads to overt hypothyroidism. Vitamin D essential for immunity. This study examines possible impacts of vitamin on the progression HT and evaluates use platelet-lymphocyte ratio (PLR) as an indicator its relationship with inflammatory process.
 Material Method: retrospective case-control study, consisting 60 i...

U937 cells respond to a variety of stimuli with increased differentiation as manifested by reduced growth. increased adherence. increased expression of several surface receptors. and increased capacity for phagocytosis and formation of reactive oxygen intermediates. In the present study the effects of lymphocyte conditioned media. recombinant interferon-’y (lFNy). and la.25-dihydroxyvitamin D3 ...

2,4.6-trinitrophenyl (TNP)-reactive T-cell activities were raised in mice by immunization with TNP-isologous mouse gamma globulin. After establishing that TNP-reactive T lymphocytes can serve as amplifier cells for induction of killer T lymphocytes in allogeneic system, we explored the possibility of this hapten-reactive T-cell system to amplify tumor-specific killer T-lymphocyte activity in th...

Bone marrow cells from C3H (H-2k) mice, a strain that does not exhibit cross-reactive lysis of trinitrophenyl (TNP)-modified allogeneic targets, were allowed to mature in heavily irradiated (B6 times C3H)F1 (H-2b/k) recipients, an F1 hybrid that does demonstrate cross-reactive lysis. Spleen cells from these chimeric mice were removed after 3-4 mo and by H-2 typing shown to be of C3H origin. The...

Lymphocyte transformation responses were studied in 21 patients with acute yersinia infection followed-up after the acute infection for up to one year. Eight patients had reactive arthritis caused by yersinia. The responses to the causative serotype of yersinia were significantly lower (p less than 0.05) in patients with arthritis than in those without arthritis. Stimulation with Escherichia co...

Lymphocytes bound at endothelial cell junctions extravasate within minutes. Lymphocyte-endothelial cell binding is mediated by receptors such as vascular cell adhesion molecule 1 (VCAM-1). VCAM-1 activates endothelial cell nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in minutes, and this activity is required for VCAM-1-dependent lymphocyte migration. In this report, we examined m...

Lymphocytes bound at endothelial cell junctions extravasate within minutes. Lymphocyte-endothelial cell binding is mediated by receptors such as vascular cell adhesion molecule 1 (VCAM-1). VCAM-1 activates endothelial cell nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in minutes, and this activity is required for VCAM-1–dependent lymphocyte migration. In this report, we examined m...

Background and Aim: Predicting high-risk patients is crucial in acute myocardial infarction (AMI). We aimed to investigate whether the leukoglycemic index (LGI) has a unique ability compare it with other inflammatory parameters predicting in-hospital mortality AMI.
 Methods: In this single-center study, we retrospectively analyzed all AMI hospitalized followed by single operator. Patients ...