PURPOSE To report the microstructural features of Meesmann corneal dystrophy (MCD) in two patients. CASE REPORT The first patient was a 10-year-old boy who presented with bilateral visual loss, diffuse corneal epithelial microcystic changes, high myopia and amblyopia. With a clinical impression of MCD, automated lamellar therapeutic keratoplasty was performed in his left eye. Histopathologic ...

A simple and consistent puncture of the anterior stroma was created with the neodymium:yttrium-aluminum-garnet (Nd:YAG) laser in a rabbit model. Varying energy levels were tested, and settings at 2.0 mJ produced well-formed anterior stromal breaks. The laser shock wave disrupted Descemet's membrane in only 1 of 50 animals. The wound healed normally in vivo over a 3-month period. Compared to nee...

In 1988 six men were referred to St Paul's Eye Hospital after the onset of acutely painful, red eyes while at work at a local sausage casing factory. These patients prepared sheep intestine for sausage skin manufacture. Ocular examination showed bilateral blepharospasm, photophobia and lacrimation, intense conjunctival injection, and superficial punctate corneal erosions. There were no other ab...

PURPOSE To report the diagnosis and management of a patient with chronic ophthalmic topical anesthetic abuse and floppy eyelid syndrome. METHODS We describe the case of a 47-year-old man suffering from persistent bilateral ocular irritation and chronic corneal erosions. RESULTS The patient was hospitalized in our ophthalmology department and underwent thorough ophthalmic, systemic, and psyc...

AIMS To evaluate the therapeutic effects of excimer laser phototherapeutic keratectomy (PTK) combined with therapeutic contact lens for painful recurrent corneal erosions (RCE) secondary to bullous keratopathy (BK) not suitable for penetrating keratoplasty. METHODS Excimer laser PTK was performed prospectively in eight eyes with painful RCE due to BK visually expecting no benefit from penetra...

OBJECTIVE Corneal collagen cross-linking with riboflavin and UV-A (CXL) decreases corneal oedema and increases visual acuity in human patients with bullous keratopathy. Presumed mechanisms are an increase in collagen packing density and a reduction in stromal swelling pressure. We present two cases in which CXL was used to treat bullous keratopathy in dogs. PROCEDURES Four eyes of two dogs wi...

PURPOSE With advances in phenotyping tools and availability of molecular characterization, an increasing number of phenotypically and genotypically diverse inherited corneal dystrophies are described. We aimed to determine the underlying causative genetic mechanism in a three-generation pedigree affected with a unique anterior membrane corneal dystrophy characterized by early onset recurrent co...

Pemphigus foliaceus (PF) is an autoimmune blistering disease presenting in endemic and sporadic forms. The typical presentation is recurrent shallow erosions in a seborrheic distribution. PF has also been found in association with autoimmune diseases such as autoimmune thyroid disease (e.g. toxic nodular goiter and Hashimoto’s thyroiditis). In some patients, PF appears to be triggered by radioi...

Soontornvipar t K. , N. Tunt ivanich, H. Kecová, P. Rau‰er :Conjunctival Pedicle Graft in Dogs and Cats: A Retrospective Study of 88 Cases. Acta Vet. Brno 2003, 72: 63-69. Seventy-eight dogs and ten cats with corneal lesions, including deep corneal stromal ulcers (n = 32), keratomalacia and recurrent erosions (n = 25), descemetocoeles (n = 18), staphylomas and perforating corneal defects (n = 5...