BACKGROUND The effect of effective refractory period (ERP) shortening on the vulnerability and characteristics of induced functional reentry in the ventricle remain poorly defined. We hypothesized that ERP shortening increases ventricular vulnerability to reentry and accelerates its rate, as is the case in the atrium. METHODS AND RESULTS The epicardial surfaces of 19 isolated and superfused c...

BACKGROUND The characteristics of transmembrane potential (TMP) at the core of functional reentry in the atrium are not well understood. METHODS AND RESULTS In protocol 1 (11 dogs), isolated perfused canine right atria were mapped from the endocardial surface while simultaneous TMPs were recorded from the epicardial surface. Episodes of reentry (n=64) were induced in the presence of 1 to 5 mi...

This article is based on an ethnographic study involving 58 Roma and Romanian participants who were released from Jilava Prion in Romania between January and July 2015. The methodology involved interviews, observation, questionnaires, and photovoice. The findings seem to suggest that most of the factors associated with desistance and reentry in the literature are relevant to the ex-prisoner's e...

Background Assessment of risk of sudden cardiac death (SCD) due to ventricular tachycardia and fibrillation (VT/VF) remains one of the most challenging areas in management of patients with chronic myocardial infarction. VT substrate consists of reentry circuits near or within a chronic scar. Invasive catheter mapping using electroanatomical system (EAM) is the clinical standard for identificati...

Alternating WEnckebach periodicity is generally believed to reflect bilevel block due to horizontal electrophysiologic dissociation in the conducting tissues. We describe a case of atrial pacing-induced atrioventricular nodal alternating Wenckebach periodicity with concealed reentry in a longitudinally dissociated AV conduction system. Three observations support this unique mechanism: Concealed...

Reentrant waves propagating in a ring or annulus of excitable media are a model of the basic mechanism underlying a major class of irregular cardiac rhythms known as anatomical reentry. Such reentrant waves are terminated by rapid electrical stimulation (pacing) from an implantable device. Because the mechanisms of such termination are poorly understood, we study pacing of anatomical reentry in...

This clinical case report describes sternal reentry performed years after adhesive-enhanced sternal closure using Kryptonite bone cement. This report provides novel data on the late effects of this innovation. We observed that sternal reentry is feasible and safe. The adhesive did not weaken from biodegradation over a period of several years. There was no evidence of adherence to adjacent soft ...

Reentry around non-conducting ventricular scar tissue, which often causes lethal arrhythmias, is typically treated by rapid stimulation from an implantable defibrillator. However, the mechanisms of termination (success and failure) are poorly understood. To elucidate such mechanisms, we studied pacing of anatomical reentry in 1-D and 2-D excitable cardiac media models. Our results suggest that ...