Renal osteodystrophy (ROD) is a multifactor disorder of bone remodelling observed in patients with chronic renal failure (CRF) from very early stages (CRF stage 2) and associated with significant morbidity. The remodelling cycle in normal bone lasts from four to eight months and includes several phases: 1) An activation phase in which osteoclasts are mobilized and activated; 2) A resorption pha...

Renal secondary hyperparathyroidism is a common sequela of chronic renal failure in the dog, but is not commonly observed in juvenile patients. A 6 month old female Labrador retriever with juvenile nephropathy and associated renal osteodystrophy is presented. Older dogs with this condition typically have highly pliable facial bones due to increased parathormone-induced osteoclastic activity sub...

BACKGROUND AND OBJECTIVES Although lesions of renal osteodystrophy have traditionally been defined by bone turnover, alterations in skeletal mineralization and volume are also prevalent and may contribute to significant morbidity in patients with chronic kidney disease (CKD). The study presented here was undertaken to compare the traditional spectrum of renal osteodystrophy defined by bone turn...

INTRODUCTION Pathological bilateral femoral neck fracture due to renal osteodystrophy is rare. This is a report of a chronic renal failure patient who had sustained bilateral intra-capsular displaced fracture neck of femur following an episode of convulsion and the difficulties encountered in early diagnosis and treatment. The pathophysiology of renal osteodystrophy and the treatment of hip fra...

Disturbances in mineral and bone metabolism are prevalent in chronic kidney disease (CKD) and are an important cause of morbidity, decreased quality of life, and extraskeletal calcification that have been associated with increased cardiovascular mortality. These disturbances have traditionally been termed renal osteodystrophy and classified based on bone biopsy. Kidney Disease: Improving Global...

An 11-year-old boy was found to have primary hyperoxaluria type I (urine oxalate 828mg/l, N 140–420mg/l). His mother had kidney stones and the parents were second degree relatives. After 18 months of dialysis, femoral neck fracture occurred, which was assumed to be related to renal osteodystrophy. During the surgical procedure to fix the fracture site internally, biopsies were taken which showe...

Summary A case of simultaneous bilateral scapula fractures and a femoral neck fracture of the right hip suffered during hypocalcemic convulsions in a 19-year-old male is presented. The medical history, the treatment, and his latest follow-up are reported. The treatment approaches of such fractures in renal osteodystrophy patients are discussed. Case report A case of simultaneous bilateral scapu...