The objective of this study was to determine the prevalence of significant lesions defined as high grade squamous intraepithelial lesions (HSIL), adenocarcinoma in situ (AIS) and invasive carcinoma in women who had HPV-positive and cytology negative co-testing screening results. This retrospective study was conducted in Chiang Mai University Hospital between May, 2013 and August, 2014. Hybrid c...

AIMS AND BACKGROUND To assess PSA use in the general population and estimate biopsy rate subsequent to opportunistic screening. METHODS AND STUDY DESIGN We report on PSA testing and related prostate biopsy frequency in the Tuscany Region during 2004-2005 to establish current patterns of care. We used population data sources to survey PSA testing and biopsy and estimated expected PSA values an...

OBJECTIVES The purpose of this study was to determine the pattern of cardiac stress testing after coronary revascularization in community practice. BACKGROUND The American College of Cardiology Foundation appropriate use criteria provide guidance for the use of cardiac stress imaging after coronary revascularization. However, little is known regarding the use of routine cardiac stress testing...

We analysed samples of 400 Finnish males using nine Y-chromosomal short tandem repeat (STR) loci (minimal haplotype); for 200 of these subjects an additional seven Y-chromosomal STR loci were used. The geographical distribution of the observed haplotypes was determined from 200 individuals of known paternal origin within Finland. The observed number of alleles varied from 2 to 13 alleles per lo...

Some rape cases result in the pregnancy of the victim and if the case is not reported to the police after the act with a subsequent gynaecological examination of the girl and the taking of a vaginal swab, there is no way of connecting the rape case with the perpetrator, except by parentage determination using DNA (deoxyribonucleic acid) analysis after abortion or induced delivery. In order to s...

Paternity tests are carried out by the analysis of hypervariable short tandem repeat DNA loci. These microsatellite sequences mutate at a higher rate than that of bulk DNA. The occurrence of germline mutations at STR loci posses problems in interpretation of resulting genetic profiles. We recently analyzed 59-159 parent/child allele transfers at 13 microsatellite loci. We identified 12 mutation...