Parameterizations of triangulated surfaces are used in an increasing number of mesh processing applications for various purposes. Although demands vary, they are often required to preserve the surface metric and thus minimize angle, area and length deformation. However, most of the existing techniques primarily target at angle preservation while disregarding global area deformation. In this pap...

Host organisms can respond to the threat of disease either through resistance defenses (which inhibit or limit infection) or through tolerance strategies (which do not limit infection, but reduce or offset its fitness consequences). Here we show that resistance and tolerance can have fundamentally different evolutionary outcomes, even when they have equivalent short-term benefit for the host. A...

Bacteria sense and respond to numerous environmental signals through two-component signaling pathways. Typically, a given stimulus will activate a sensor histidine kinase to autophosphorylate and then phosphotransfer to a cognate response regulator, which can mount an appropriate response. Although these signaling pathways often appear to be simple switches, they can also orchestrate surprising...