BACKGROUND The physiological changes of pregnancy may predispose females to develop restless legs syndrome (RLS). Studies evaluating outcomes of RLS symptoms in pregnancy are scarce. OBJECTIVES We examined the risk of preterm birth in pregnant women with and without restless legs syndrome (RLS). MATERIALS AND METHODS A cohort study included 231 pregnant women attending Ardabil health care c...

OBJECTIVE Restless legs syndrome (RLS) is a distressing sleep disorder to which individuals appear to be genetically predisposed. In the present study, we assumed that antipsychotic-induced RLS symptoms were attributable to differences in individual genetic susceptibility, and investigated whether MEIS1, a promising candidate gene, was associated with antipsychotic-induced RLS symptoms in schiz...

Background Restless legs syndrome (RLS) in children is commonly reported, yet frequently undiagnosed. RLS can cause significant sleep disturbance and its associated deficits may have cardiovascular and neurocognitive consequences. Growing pains (GP) is often confused or synonymous with RLS, yet has been better researched and can be identified by parental questionnaire. RLS has not been able to ...

INTRODUCTION Restless legs syndrome (RLS) affects 5-15% of adults, but is often unrecognized and consequently misdiagnosed. The International Restless Legs Scale (IRLS) has been developed and validated to assess the severity of RLS. Currently, the most common treatment for RLS is levodopa, but this may lead to augmentation of symptoms. Pramipexole has been developed as an alternative treatment ...

OBJECTIVES Subjective sleep complaints have been reported in up to 80% of patients with end stage renal disease (ESRD). In these patients, sleep disturbances manifesting as insomnia, sleep apnea syndrome, restless leg syndrome (RLS), periodic limb movement disorder and excessive daytime sleepiness (EDS) have been frequently reported. Moreover, studies about the role of dialysis shift on sleep a...

Background. Restless legs syndrome (RLS) is a sleep disorder characterized by an urge to move or the presence of unpleasant sensations in the extremities. The prevalence of RLS is higher in children and adults with chronic kidney disease and in adults with glomerular disease. Objective. To determine the prevalence of RLS in children with nephrotic syndrome. Methods. We studied 50 children with ...

Sleep problems have been making a lot of news. Some sleep experts suggest that most Americans do not get as much sleep as they need. Lack of sleep, or lack of good quality sleep, affects the way we think, our relations with others, and our general health. There are many reasons and causes for poor sleep, including outside causes (loud noises) and internal causes (pain, stress, breathing trouble...

BACKGROUND Sleep disturbances, in particular restless legs or limb movements, during the night are often reported by uremic patients. However, polysomnography (PSG) studies have never been carried out to confirm the actual occurrence of these disorders and the association with other objective and self-reported sleep-wake data. METHODS Forty-eight participants were subjected to a 2-day PSG. Th...

BACKGROUND Restless legs syndrome (RLS) is a common disorder in hemodialysis patients that leads to insomnia and impaired quality of life. Because high oxidative stress has been implicated in the pathogenesis of RLS, we sought to evaluate the efficacy of vitamins C and E and their combination in reducing the severity of RLS symptoms in hemodialysis patients in this randomized, double-blind, pla...

Restless Legs Syndrome (RLS) is a common movement disorder characterized by a circadian variation in symptoms involving an urge to move the limbs, usually the legs. Pregnant women, patients with end-stage renal disease or iron-deficiency anemia, and children with attention deficit hyperactivity disorder (AD/HD) have a significantly higher prevalence of RLS. The classic presentation includes the...