نتایج جستجو برای: reteplase
تعداد نتایج: 161 فیلتر نتایج به سال:
OBJECTIVES We hypothesized that patients most likely to benefit would be those at high risk with a shorter duration of acute ischemia and who required transfer for percutaneous coronary intervention (PCI). BACKGROUND The FINESSE (Facilitated Intervention with Enhanced Reperfusion Speed to Stop Events) study failed to demonstrate an improvement in the 90-day composite clinical end point of ear...
BACKGROUND Thrombolysis remains the treatment of choice in ST-segment elevation myocardial infarction (STEMI) when primary percutaneous coronary intervention (PCI) cannot be done within 90 min. However, the best subsequent management of patients after thrombolytic therapy remains unclear. To assess the best management, we randomised patients with STEMI treated by thrombolysis and abciximab at a...
A 61year old man on chronic aspirin treatment with unstable angina was admitted to our hospital to undergo programmed percutaneous coronary artery angioplasty. A balloon angioplasty (with a 3.5 mm diameter balloon) to a type B lesion in the proximal LAD was performed, and a stent (4.0 x 16mm stent) was implanted because of a dissection producing acute vessel occlusion. During the procedure 5000...
OBJECTIVES This study was undertaken to assess prospectively the prognostic power of early ST segment elevation resolution in a large cohort of patients with myocardial infarction and to test the value of differences in ST segment resolution as a surrogate end point. BACKGROUND Previous studies revealed that the use of two cutoff points for three groups of ST segment resolution within 3 h aft...
Reteplase (rPA) is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome. Though methanol induction of the native and the rPA mutants showed similar expression levels (~200-250 mg/L), the mutants displayed significant loss of protease activity. Strikingly, the clot...
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