Multiple functions of methyl-deficient tRNAMet, including those specific for initiator tRNA, were investigated and compared with normal tRNAMet. A comparison of the chromatographic properties of normal and methyl-deficient methionyl-tRNA showed identical elution profiles on methylated albumin-Kieselguhr, benzoylated o-(diethylaminoethyl)cellulose, and reverse phase chromatography (isoamylacetat...

effects of temperature and percentage of organic modifier were studied on retention and selectivity in rp-hplc using solvation parameter model. the system constants were determined by multiple linear regression analysis from experimental values in the retention factor for a group of different solutes with known descriptors by computer using the program spss/pc. the experimental results showed t...

Abbreviations: FVIII/vWF: Complex of Factor VIII and von Willebrand Factor; MW: Molecular Weight; NDF: Number of Degree of Freedom; S/D: Solvent/Detergent; LEV/LEVs: Virus (es) Enveloped by Lipid Membrane; NLEV/NLEVs: Non-enveloped Virus (es); IFA method: Method of Immune-fermental Analysis; FITC: Fluorescein Isothiocyanate; RT-PCR method: Real-time PCR Method; TCID50: 50% Tissue Culture Infect...

304 CLINICALCHEMISTRY,Vol.38, No.2, 1992 chain length on protein retention, resolution, and recovery implications for preparative HPLC. J Liq Chromatogr 1983;6:497-510. 4. Tarr GE, Crabb JW. Reverse-phase high-performance liquid chromatography of hydrophobic proteins and fragments thereof. Anal Biochem 1983;131:99-107. 5. Wu D, Walters ER. Stationary-phase ligand density effects in reversed-pha...

A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...

A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...

effects of temperature and percentage of organic modifier were studied on retention and selectivity in rp-hplc using solvation parameter model. the system constants were determined by multiple linear regression analysis from experimental values in the retention factor for a group of different solutes with known descriptors by computer using the program spss/pc. the experimental results showed t...