Rheumatological syndromes are generally chronic and this is often reflected in the onset and persistence of symptoms such as pain, whose physiopathological characteristics may change over time. It has been known for some time that as many as 15-30% of patients with classic autoimmune or rheumatic disorders also have a comorbid fibromyalgia syndrome (FMS). As these rates are much higher than the...

There are multiple interactions between rheumatology and oral medicine. Three overlapping areas will be covered in this lecture: (1) Oral manifestations of rheumatic disease. Several rheumatic diseases have prominent manifestations in the oral cavity, head and neck. Because these manifestations tend to be nonspecific, the underlying condition may go unrecognized unless the oral surgeon suspects...

some relevant to all twin studies and some particular to chronic diseases. The " Bible " of gemellology is " Twins in History and Science " by Louis Gedda (1961), which covers all aspects including a review of twins in Mythology and history. From Castor and Pollux to the Kray Brothers, twins have tended to attract more than their fair share of attention. Twin pairs are of three sorts (a) monozy...

Amyloidoses represent an inhomogeneous group of diseases characterized by extracellular deposition of amyloid fibrils. AA amyloidosis is a serious life-threatening complication of chronic rheumatic diseases responsible for increased mortality due to organ failure or infection. The main component of amyloid is the serum amyloid A precursor protein (SAA) produced by the liver as an acute phase pr...

233. London: John Lane. 1905. This newest work on rheumatic affections is founded entirely 011 the belief that rheumatic conditions are incited by a specific micro-organism, the diplococcus rheumaticus. It is further maintained that in the chronic forms of rheumatism, and in acute and chronic rheumatoid arthritis, the exciting cause is a modified or a virulent form of the coccus of acute rheuma...

Uveitis occurs among children suffering from juvenile chronic arthropathy (mainly in daughters presenting with the pauciarticular form and accompanied by antinuclear antibodies) and among adults in the group of seronegative spondylarthropathies, among which ankylosing spondylitis and Reiter's syndrome are the most representative diseases. The association between acute anterior uveitis, HLA B27 ...

Until recently, patients with chronic autoimmune diseases were dying at a young age from their disease. However, with the emergence of biologic drugs and disease-targeted therapies, longevity in this patient population has increased. In addition, physicians have become more aware of the long-term sequelae of chronic inflammation focusing mainly on the development of premature atherosclerosis. I...

"Someone to look after the whole patient, not just the part that hurts" was how one consultant summarised the medical needs of patients with rheumatic disease. Another described rehabilitation as pulling together the relevant information and pointing the patient in the right direction-for much is known and much is available. Yet both patients and general practitioners tend to have low expectati...

1 Center for Autoimmune Diseases Research (CREA), Universidad del Rosario, Carrera 24 No. 63C-69, 111221 Bogota, Colombia 2 ZabludowitczCenter forAutoimmuneDiseases, ShebaMedical Center, Tel-Hashomer, Sackler Faculty ofMedicine, Tel AvivUniversity, 52621 Tel-Hashomer, Israel 3 Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Charitéplatz 1, 10117 Berlin, Germany 4...