Nutritional rickets is a major public health problem in many countries of the world. The disease is characterized by deformities of the long bones, enlargement of the wrists and costochondral junctions, hypotonia and, in infants, craniotabes and delayed fontanelle closure. Predominantly caused by severe vitamin D deficiency, rickets can also be associated with hypocalcemic seizures and cardiac ...

Rickets which is refractory to ordinary doses of vitamin D was first recognized when vitamin preparations of high potency became available (Albright, Butler and Bloomberg, 1937). As an isolated metabolic disorder it is commonly known as 'vitamin D-resistant rickets', also as 'phosphate diabetes' (Fanconi, 1936a, b) and phosphate losing(or renal tubular) rickets, type I (Dent, 1952). Whereas it ...

OBJECTIVE The study on sub clinical rickets is unique in the sense that it has not been preplanned conducted anywhere especially in Pakistan. The objective of present study was to explore the prevalence, gender and geographical distribution of sub clinical rickets and their related factors among school students. METHODS Out of total participants, 189(90%) students were finally included in the...

BACKGROUND Reports of osteopaenia/rickets of prematurity are on the increase due to improved survival rates of low birthweight infants. OBJECTIVE To establish the incidence of rickets of prematurity by the age of six months in premature infants born at Kenyatta National Hospital, Nairobi. DESIGN Prospective cohort study. SETTING Newborn unit and paediatric outpatient follow up clinic of K...

This review was conducted to study the diagnosis, treatment, and growth progression in infants and adolescents with familial hypophosphatemic rickets. The bibliographic search was carried out utilizing the electronic databases MEDLINE, OVID, and LILACS and by direct research within the last 15 years using the keywords rickets, familial hypophosphatemia, vitamin D deficiency, stature growth, chi...

1. Rickets developed in three puppies deprived of vitamin D and sunlight since birth, in which, at the age of 6 to 7 weeks gall bladder fistula was established. The results of studies of their bones and of the calcium and phosphate metabolism have previously been published (2). Studies on the nitrogen, potassium, sodium, and chlorine metabolism, here presented, reveal that the metabolism was gr...

At Ataturk University Hospital, eight infants who presented with hypocalcaemic seizures were subsequently found to have rickets. Their mothers had osteomalacia. Neither mothers nor infants received vitamin D supplementation. Maternal vitamin D deficiency and non-supplementation in the infants were causes of rickets in these patients. It is recommended that neonatal hypocalcaemia may be due to m...

An infant with chronic cytomegalovirus hepatitis and a child with atypical Alagille's syndrome had vitamin D deficiency rickets due to malabsorption. Both received ultraviolet irradiation. This treatment corrected biochemical abnormalities and healed the rickets. In the infant use of a sunlamp at home maintained normal 25 hydroxy-vitamin D for over a year. Our study shows that ultraviolet irrad...

background: metabolic bone diseases (mbd), including rickets and osteopenia, are important neonatal complications among preterm infants. this study aimed to determine the prevalence and risk factors of mbd in neonates with very low birth weight (vlbw). methods: this prospective study was conducted on vlbw infants from january 2012 to july 2013. inclusion criteria were birth weight of ≤1500 g an...