Anaesthetic requirements for nitrous oxide, enflurane and isoflurane were determined in mice selectively bred for their susceptibility ("long-sleep" mice) or resistance ("short-sleep" mice) to alcohol. Nitrous oxide and enflurane requirements, measured by the rolling-response test, were 34 and 20% greater, respectively, in short-sleep mice than in long-sleep mice. Although isoflurane requiremen...

Abstract Laser cladding is a new surface repair method that can improve the wear and corrosion resistance of substrate surfaces. However, layer typically exhibits rough surface, high hardness large residual tensile stress, thus requires further machining finishing. Ultrasonic rolling (U-rolling) highly efficient finishing strengthening process combines ultrasonic technology with traditional (T-...

Phenomenological approach to the description of deformation resistance behaviour of steel and its microstructure development under the service hot rolling condition is still the most common useful and powerful. Utilising different experimental equipment such as torsion plastometer [1-5], compression plastometer [6-9], or advanced laboratory mills [10, 11] as well as different deformation techni...

Selectins are a family of lectins that mediate tethering and rolling of leukocytes on endothelium in vascular shear flow. To test the hypothesis that the kinetics and the strength of rolling interactions can be independently varied for different selectin:ligand pairs, we have directly compared all three selectins with regard to distinct measures of selectin-mediated interactions in shear flow: ...

Selectin interactions with glycolipids have been examined previously under static conditions, whereas physiologic interactions mediated by selectins take place under flow. We find that under physiologic flow conditions, sialyl Lewis(x) (sLe(x)) glycolipid and sialyl Lewisa (sLe(a)) neoglycolipid support tethering and rolling adhesions of Chinese hamster ovary (CHO) cells expressing E-selectin a...

The aim of this review is to survey the state of the art relating to the rolling contact fatigue (RCF) investigation of various overlay coatings and also, to ascertain the influence of design parameters such as the type of deposition process, coating material and thickness on the RCF performance. Rolling contact fatigue is a significant factor in the failure of components in rolling/sliding con...

Using contact measurements, experimental evidence was obtained for the existence of the rolling resistance moment. The critical rolling distance prior to detachment is reported. Previously it has been argued that the critical rolling distance should be related to the lattice size and/or the molecular length of the particle and surface materials. However, there has been no theoretical prediction...