BACKGROUND Polycystic ovary syndrome (PCOS) is a common condition in women of reproductive age. It is characterized by hyperandrogenism, oligomenorrhea/amenorrhea and polycystic ovaries. It is associated with obesity, diabetes, dyslipidemia and cardiovascular disease. No studies have been conducted on the prevalence of PCOS in Brazilian or South American women. Few studies using the Rotterdam c...

Polycystic ovary syndrome (PCOS) is found in 3 to 6% of women in child-bearing age. At the same time PCOS is the most common cause of infertility. The diagnostic criteria for PCOS include: anovulation or ovulatory disorders, hyperandrogenism and typical polycystic ovary image in ultrasound examination in the absence of other causes of hyperandrogenism. The etiology of the syndrome remains unkno...

Objective. Recent reports warn that the worldwide cell culture capacity is insufficient to fulfill the increasing demand for human protein drugs. Production in milk of transgenic animals is an attractive alternative. Kilogram quantities of product per year can be obtained at relatively low costs, even in small animals such as rabbits. We tested the long-term safety and efficacy of recombinant h...

1. Department of Interventional Cardiology, Erasmus Medical Center, Thoraxcenter Rotterdam, The Netherlands 2. Cardialysis BV, Rotterdam, The Netherlands 3. Department of Cardiothoracic Surgery, Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands 4. Institut Cardiovasculaire Paris Sud, Massy, France 5. San Raffaele Hospital, Milano, Italy 6. Southampton General Hospital, Southampto...

Polycystic ovary syndrome is a multi-factorial disease. Its etiopathogenesis has not been elucidated in detail. It is the most common endocrine disorder in women of child-bearing age. This disease entity is primarily characterized by disrupted ovulation and hyperandrogenism, but the clinical picture can be diversified and symptom intensity can vary. Currently, the sonographic assessment of ovar...

Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands, Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center, Rotterdam, Netherlands, Department of Psychiatry, Erasmus Medical Center, Rotterdam, Netherlands, Department of Epidemiology, Eras...

Background: The present research explores the correlation of visceral obesity index with Rotterdam criteria (hyperandrogenism and/or hyperandrogenemia, oligomenorrhea and Ultrasound polycystic ovarian morphology) among Egyptian polycystic ovary syndrome patients. Methods: We enrolled one hundred female patients with polycystic ovary syndrome with age ranged 18-44 years (mean age 26.83±6.092 yea...