INTRODUCTION: Niclosamide is in the antihelminthic family especially effective against cestodes that infect humans. It is also used as a pesticide. , Niclosamide is used specifically to treat tapeworms and is not effective against other worms such as pinworms or roundworms. IUPAC name for Niclosamide is 5-chloro-N-(2chloro-4-nitrophenyl)-2-hydroxybenzamide, molecular weight is 327.119 g/mol, an...

findings were obscured by excessive bowel gas and demonstrated dilated bowel loops and probable volvulus of the small bowel. The child was adequately resuscitated with intravenous fluids, antibiotics and red cell transfusion. As the child was critically ill, no further imaging was done. Once stabilized, an exploratory laparotomy was performed which revealed the jejunum and ileum filled with 150...

More than 300 million people suffer from a range of diseases caused by gastropod-borne helminths, predominantly flatworms and roundworms, whose life cycles are characterized by a diversified ecology and epidemiology. Despite the plethora of data on these parasites, very little is known of the fundamental biology of their gastropod intermediate hosts, or of the interactions occurring at the snai...

Trichinellosis is a globally important food-borne parasitic disease of humans caused by roundworms of the Trichinella complex. Extensive biological diversity is reflected in substantial ecological and genetic variability within and among Trichinella taxa, and major controversy surrounds the systematics of this complex. Here we report the sequencing and assembly of 16 draft genomes representing ...

Genes throughout development govern synaptic transmission and, thus, neuronal excitability in both roundworms and humans. Notably, malfunction of synaptic vesicle targeting through the absence of essential regulatory proteins often leads to neurological dysfunction. Experimental results from our laboratory demonstrate that mutations or RNA interference (RNAi) against synaptic vesicle targeting ...

Aim: To determine the frequency of worm infestation among the children of Union Council Mangri, Tehsil Shakargarh, District Narowal. Methodology: It was cross-sectional descriptive study conducted on 97 children living in Union Council Mangri, Tehsil Shakargarh, District Narowal using non-probability convenient sampling. Pretested questionnaire was used to collect demographic data and microscop...

Toxocara species are most common roundworms of Canidae and Felidae. Human toxocariasis develops by ingesting of embryonated eggs in contaminated soil. There is no previous report of Toxocara contamination in the soil samples from the public areas in Bangkok. For this reason our study have been carried out to examine the frequency of Toxocara eggs in public yards in Bangkok, Thailand. A total of...

Toxocariasis is a preventable parasitic disease that is caused by the dog and cat roundworms Toxocara cani and T. cati, respectively. Humans become infected when they accidently ingest infectious Toxocara eggs commonly found in contaminated soil; children are most often affected. Clinical manifestations of Toxocara infection in humans include ocular toxocariasis and visceral toxocariasis. Altho...

Although the ability to detect humidity (i.e., hygrosensation) represents an important sensory attribute in many animal species (including humans), the neurophysiological and molecular bases of such sensory ability remain largely unknown in many animals. Recently, Russell and colleagues (Russell J, Vidal-Gadea AG, Makay A, Lanam C, Pierce-Shimomura JT. Proc Natl Acad Sci USA 111: 8269-8274, 201...

mopolitan roundworms that infect dogs, especially puppies, and cats. T. canis infection in humans occurs by ingestion of the embryonic eggs, which are shed in the feces of infected dogs. Toxocariasis is manifested in three different syndromes: visceral larva migrans (VLM), ocular larva migrans (OLM), and covert toxocariasis (1, 2). VLM is usually a disease of children 1 to 6 year old, and it ma...