نتایج جستجو برای: route of administration
تعداد نتایج: 21178369 فیلتر نتایج به سال:
Introduction: surgical site infection is one of the most important causes of mortality and morbidity: use of the prophylactic antibiotic is one of the effective methods for its prevention, the present study aimed to investigate the status of prophylactic administration of antibiotics in Surgery Department of Shahid Sadoughi Hospital of Yazd City in 2018. Methods: this descriptive cross-section...
lactobacilli, like the other gut commensal bacteria, are well known for their use in poultry nutrition and for their probiotic properties. however, little is known about their interaction with the gastro-intestinal tract when administered in vivo. to specifically monitor the passage of lactobacilli after administered in hatchery, lactobacillus plantarum was transformed with the recombinant vect...
Intraarterial chemotherapy with Adriamycin (ADM) has shown limited advantages over i.v. administration, with no reduction in systemic toxicities and modest decrease in peripheral plasma levels. In an effort to improve the selectivity of i.a. anthracycline chemotherapy, we compared pirarubicin (4'-O-tetrahydropyranyladriamycin, THP) and ADM in the surgically implanted VX2 rabbit tumor model. Bot...
Several challenges are associated with current vaccine strategies, including repeated immunizations, poor patient compliance, and limited approved routes for delivery, which may hinder induction of protective immunity. Thus, there is a need for new vaccine adjuvants capable of multi-route administration and prolonged antigen release at the site of administration by providing a depot within tiss...
Background: Major depressive disorder is a severe, heterogeneous, common medical illness and a leading cause of disability throughout the world that poses a significant public health issue. Previous studies have shown rapid antidepressant effects following a single administration of ketamine. This study aimed to assess the impact of route of administration and dose of ketamine for the reduction...
The buccal route does not have any disadvantages when compared to the oral route of prostaglandin administration. The incidence of vomiting (25%) described for the oral route by other workers is similar.2 3 The buccal route also has the advantages of oral drug administration. These are staff convenience and patient comfort, the latter being without the discomfort of an intravenous infusion and ...
Objective(s): Renal ischemia-reperfusion injury (IRI) as a severe condition of acute kidney injury (AKI) is the most common clinical problem with high mortality rates of 35-60% deaths in hospital. Mesenchymal stem cells (MSC) due to unique regenerative characteristics are ideal candidates for the treatment of the ischemic injuries. This work is focused on the administration of MSC to IRI-induce...
BACKGROUND Palonosetron is a potent second generation 5- hydroxytryptamine-3 selective antagonist which can be administered by either intravenous (IV) or oral routes, but subcutaneous (SC) administration of palonosetron has never been studied, even though it could have useful clinical applications. In this study, we evaluate the bioavailability of SC palonosetron. PATIENTS AND METHODS Patient...
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