The biosynthesis of some furocoumarins present in Ruta graveolens has been studied administering labeled psoralen, xanthotoxin, rutaretin, marmesin and 7-hydroxycoumarin-derivatives. The results obtained indicate that the biosynthetic pathway involves not only psoralen, but also xanthotoxin and bergapten, by means of methoxylation or demethoxylation reactions. Moreover results achieved from adm...

Acridone synthase has been purified from cell suspension cultures of Ruta graveolens using a combination of gel filtration and ion exchange chromatography. The purified enzyme has an apparent molecular weight of 69 kDa on gel filtration and a subunit structure on SDS-PAGE of 40 kDa. The apparent Km-values are 10.64 microM and 32.8 microM for N-methylanthraniloyl-CoA and malonyl-CoA, respectivel...

the antioxidant properties of ruta graveolens l. were evaluated by two different methods; free radical scavenging using dpph and inhibition of lipid peroxidation by the ferric thiocyanate method. the ic50 value of the methanol extract in dpph inhibition was 200.5 μg/ml which was acceptable in comparison with bht (41.8 μg/ml). in thiocyanate method, the plant extract demonstrated activity as muc...

Antimicrobial screening against selected Gram-positive and Gram-negative bacteria, yeasts, mold, as well as plant pathogenic fungi, with emphasis on method optimization was carried out on methanol extracts prepared from seven plants grown in Finland. Sensitivity to the extracts was found to vary considerably among the micro-organisms, the extract from Petroselinum crispum and Ruta graveolens sh...

A young lady applied herbal mask of common rue (Ruta graveolens) onto her face. After that, she took a nap on a balcony in the full sun. An hour later, she woke up with a burning sensation, erythema and oedema of the skin. A few hours later, painful erythema and oedema developed. Subsequently, she developed a bullous reaction, which became superinfected in the following days. After treatment of...

a LIBIQUIMA, Facultad de Ingeniería, IDEPA, Universidad Nacional del Comahue – CONICET, Buenos Aires 1400, 8300 Neuquén, Argentina b Facultad de Ciencias Agrarias, Universidad Nacional del Comahue, Ruta 151 Km 12.5, 8303 Cinco Saltos, Río Negro, Argentina c Facultad de Ciencias Médicas, Universidad Nacional del Comahue, Toschi y Arrayanes, 8324 Cipolletti, Río Negro, Argentina d Laboratorio de ...

M. I. Petaev, A. Meibom, C. Perron, and B. Zanda, Dept. of the Geophysical Sciences, University of Chicago (5734 S. Ellis Ave., Chicago, IL 60637 USA; [email protected]), Dept. of Earth and Planetary Sciences, Harvard University (20 Oxford St., Cambridge, MA 02138 USA; [email protected]), Dept. of Geological and Environmental Sciences, Stanford University (Building 320, Lomita Mall,...