brown tumors may occur secondary to hyperparathyroidism in patients with chronic renal failure (ckd). they are increasingly rare because hyperparathyroidism in now diagnosed and treated at an early stage. we report 67-year-old man who had been on hemodialysis for crf for over 3 years, who presented with back pain over the thoracolumbar junction from 2 years ago and because of pain he could not ...

background: invasive ductal carcinoma is the most common type of breast cancer in iran. impaired immune responses occur frequently in cancer patients, but the mechanisms of the induced immune defects remain poorly understood. it is believed that infiltrated immune cells, especially macrophages, may provide help for tumor cell growth and metastasis.   objective: to analyze the status of tumor as...

objective(s): the goal of this study was assessing the prophylactic effect of exercise and its role as an adjuvant therapy on level of cytokines involved in angiogenesis in estrogen-dependent breast cancer. materials and methods: forty female balb/c mice were randomly assigned to exercise-tumor-exercise (ete), exercise-tumor-rest (etr), rest-tumor-exercise (rte) and rest-tumor-rest (rtr) groups...

introduction: a keratocystic odontogenic tumor is a benign intra-bone mass originating from dental lamina or its residue. it represents 2–11% of jaw cysts, and has a slow but aggressive growth. the evaluation of molecular characteristics, immunohistochemistry, and genetic expression currently have no established classification regarding the evolution and pathophysiologic pattern of these lesion...

conclusions pnet/ews should be included in the differential diagnosis of renal tumors in symptomatic young adults. patients with localised pnet/ews treated with a combination of surgery and chemotherapy have an excellent chance of long-term survival, as in the case we have presented. introduction primitive neuroectodermal tumor (pnet)/ewing’s sarcoma (ews) belongs to a family of neoplasms that ...

introduction:neurogenic mediastinal tumors comprise a wide range of benign and malignant diseases. a group of these tumors, located at thoracic apex, sometimes spread to cervical spaces causing numerous surgical difficulties. in thoracotomy approaches, due to proximity of the tumors to major blood vessels, complete removal of these tumors from cervical spaces is impossible or may cause intraope...

introduction: different imaging modalities are used to evaluate salivary gland diseases, including tumors. ultrasonography (us) is the preferred method on account of its ease of use, affordability, safety profile, and good tolerance among patients. the aim of this study was to evaluate the role of us in differentiating malignant from benign parotid tumors, in the context of previous controversy...

introduction: notochord. although histologically benign, these tumors are locally aggressiveand present significant managment challenges . there arew some studies onevaluated the location, age and gender of the patients with chordoma in tworeferral centers in tehran.chordoma cases but there was no study about iranian cases. in this study weskull base chordomas are rare neoplasms arising from th...

Objective(s): The OCT4B1, as one of OCT4 variants, is expressed in cancer cell lines and tissues more than other variants and plays an important role in apoptosis and stress (heat shock protein) pathways. The present study was designed to determine the effects of OCT4B1 silencing on expressional profile of HSP40 gene family expression in three different human tumor cell lines. Materials and Met...

Objective(s): Low penetration depth of light is the main defect of photodynamic therapy (PDT), which could be improved by sonodynamic therapy (SDT). In this study, a combination of PDT and SDT known as sonophotodynamic therapy (SPDT) was investigated using two reverse arrangements in CT26 tumor model. Materials and Methods: The liposomal zinc phthalocyanine was synthesized and characterized. It...