Coastal areas in Southeast Asia are experiencing high sodium concentrations in drinking water sources that are commonly consumed by local populations. Salinity problems caused by episodic cyclones and subsequent seawater inundations are likely (partly) related to climate change and further exacerbated by changes in upstream river flow and local land-use activities. Dietary (food) sodium plays a...

Angiotensin I converting enzyme inhibitors are typically classified as peripheral vasodilators. We studied the effect of captopril and a known vasodilator, hydralazine, on arterial pressure-urinary output relationships in adult spontaneously hypertensive rats to determine whether these drugs produced similar changes in this relationship. Tail-cuff pressure and 24-hour urine output and sodium ex...

background and aims. as a result of poor quality of public water supply in many countries, people have recently turned to bottled water consumption, the fluoride content of which is not generally consistent among different brands. this study sought to measure the fluoride concentration of public water supply in comparison with commercial brands of mineral bottled water available in tehran, iran...

To examine the behavioral and neural control of body fluid homeostasis, water and saline intake of C57BL/6 mice was monitored under ad libitum conditions, after treatments that induce water or salt intake, and after ablation of the periventricular tissue of the anteroventral third ventricle (AV3V). Mice have nocturnal drinking that is most prevalent after the offset and before the onset of ligh...

drinking water quality can be deteriorated by microbial and toxic chemicals during transport, storage and handling before using by the consumer. this study was conducted to evaluate the microbial and physicochemical quality of drinking water from bottled water coolers.a total of 64 water samples, over a 5-month period in 2012-2013, were collected from free standing bottled water coolers and wat...

Introduction: Zinc is an essential trace element that plays an important role in the synaptic plasticity and modulation of the CNS activity and is also involved in learning and memory. Synaptic vesicle zinc in the hippocampus area exerts modulatory effects on NMDA glutamate receptors. Methods: In this study, the effects of intra hippocampal administration of NMDA agonist and antagonist in the p...

This work examined the effects of age on salt appetite measured in the form of daily saline (i.e., 0.3 M NaCl) drinking in response to administration of deoxycorticosterone acetate (DOCA; 5 mg/kg body wt) using young (4 mo), "middle-aged" adult (12 mo), and old (30 mo) male Brown Norway rats. Water and sodium intakes, excretions, and balances were determined daily. The salt appetite response wa...

statement of the problem generally, the main source of fluoride intake is drinking water. excessive consumption of bottled water as a substitute or in addition to the tap water supply may have implications for safe fluoride supplementation. in this study, fluoride contents in six commercial brands of bottled water were measured materials and methods six different brands of bottled drinking wate...

Pretreatment with morphine-like agonists potentiates the behavioral effects of opioid antagonists, possibly reflecting a state of acute physical dependence. Several studies have used operant behavior to quantify these effects. However, little research has been done using unconditioned behavior. One objective of this study was to determine whether opioid agonist pretreatment (e.g., morphine, fen...

Historical accounts of alcohol administration to patients with breathing problems suggest that alcohol may have bronchodilating properties. We hypothesized that acute alcohol exposure will alter airway responsiveness (AR) in mice. To test this hypothesis, C57BL/6 mice were fed either 20% alcohol in drinking water (fed) or received a single intraperitoneal (ip) injection of alcohol (3 g/kg). Con...