Mouse submandibular salivary gland cells and liver progenitor cells from long-term in vitro cultures with a high proliferation potential were side-by-side compared by methods of immunocytochemistry, quantitative real-time PCR, flow cytometry, and transcriptome analysis. The two cell types were found to be similar in expressing cell markers such as EpCAM, CD29, c-Kit, Sca-1, and c-Met. In additi...

Tumors of the salivary glands constitute an important field of oral and maxillofacial pathology. The majority of salivary gland neoplasms are benign, with malignant salivary tumors accounting for 15 to 32 percent. The most common site for salivary gland tumors is the parotid gland, accounting up to 80 percent of all cases. This article reports the pathologic picture in a case of sebaceous adeno...

Sclerosing polycystic adenosis of the major salivary glands is rare and can simulate a slow growing tumour. It is pseudoencapsulated and includes tubuloacinar adenosis with dilated ducts, apocrine metaplasia, epithelial hyperplasia, and cystic changes associated with fibrosis. The histological appearance of the lesion is similar to that of fibrocystic disease of the breast. The multifocal natur...

objective: e-cadherin is a classic cadherin that plays a key role in epithelial cell adhesion. this protein is being referred to as the suppressor of proliferation and invasion. limited studies have investigated e-cadherin expression in salivary gland neoplasms. this study sought to assess the expression of e-cadherin and its possible role in progression and invasion of salivary gland neoplasms...

ber of the ENaC/degenerin family of non-voltage gated ion channels. ENaC is localized in the apical membrane of epithelial cells, and is the rate limiting step for sodium absorption in a number of epithelial tissues like the aldosterone-sensitive distal nephron (ASDN), respiratory epithelia, distal colon, sweat and salivary ducts. ENaC is probably a heterotrimer with three well characterized su...

The present study was conducted to describe the histological features of parotid and submandibular salivary glands of European hamster. The glands samples were obtained from five adult males and microscopic slides were prepared using routine histological technique. The results showed that these glands divide in lobes associated with the ducts. The parotid was a typical serous gland, but the sub...

Mucocele forms because of salivary gland mucous extravasation or retention and is usually related to trauma in the area of the lower lips. Ruptured ducts release the mucous that accumulates into adjacent tissues, leading to swelling. This report describes a large mucocele involving the lower lip, which was produced in a child by incorrect use of a pacifier. A few important concepts are discusse...

We report a rare case of dry eyes and dry mouth caused by primary amyloidosis. A 66-year-old woman with keratoconjunctivitis sicca and xerostomia died of acute respiratory failure. Shirmer's test, gum test, and sialography indicated Sjögren's syndrome. Lip biopsy revealed amyloid deposition around the salivary ducts. Bence-Jones protein was noted in the urine. At autopsy, amyloid deposition was...

Inflammation of the salivary gland is a well-documented aspect of salivary gland dysfunction that occurs in Sjogren's syndrome (SS), an autoimmune disease, and in γ-radiation-induced injury during treatment of head and neck cancers. Extracellular nucleotides have gained recognition as key modulators of inflammation through activation of cell surface ionotropic and metabotropic receptors, althou...