BACKGROUND Saliva plays a critical role in maintaining oral homeostasis; it modulates the ecosystem through lubrication of the alimentary bolus, protection against microorganisms, buffer and repair of the oral mucosa, and helps in dental re-mineralization. Various local and systemic factors such as medications, radiation therapy, systemic conditions, etc. can lead to reduction in salivary flow....

OBJECTIVES The aim of this study was to identify changes in the oral environment with clinical, salivary and bacterial risk markers after placement of fixed orthodontic appliances on permanent dentition. MATERIAL AND METHODS With ethical approval, we used different techniques to analyzed clinical, salivary and bacterial risk markers in 34 patients (mean age, 16.7+5.2 years), 14 males and 20 f...

Objective: Diabetes Mellitus is one of the most common metabolic disorders which have several oral complications such as hypofunction of salivary glands. The aim of present study was to compare the unstimulated whole saliva (UWS) flow rate in diabetic type II patients and healthy peoples who admitted in Yazd Diabetic center. Materials and Methods: In this analytic-observational study, 78 patie...

Purpose: To investigate inter- and intra-individual variation in the levels outputs (concentration multiplied by salivary flow rate) of metabolites patients with primary Sjögren’s syndrome (pSS).

Modeer T. et al.(2011) claim that there is association between decreased salivary flow rate and caries in obese adolescents. The aim of this study was to determine the association among nutritional status, salivary flow rate and caries risk in preschoolers. The study comprised 60 children aged 3 to 6 years attending kindergartens in areas immediately adjacent to Buenos Aires City, Argentina. Bo...

Introduction. Decreased salivary flow and xerostomia are frequent findings in Parkinson's disease (PD), possibly caused by alterations in the parasympathetic tonus. Here we explore salivary acetylcholinesterase (AChE) activity as a potential biomarker in PD. Methods. We measured salivary flow, AChE activity, and total protein concentration in 30 PD patients and 49 healthy controls. We also perf...

Elderly people, especially those institutionalized in long-term care facilities, are at risk of various oral diseases. The aim of the study was to determine the incidence of hyposalivation and colonization/oral fungal infection of oral cavity with yeasts, as well as dental status in institutionalized and non-institutionalized elderly. The study included 280 institutionalized and 61 non-institut...