Description of Procedure or Service Populations Interventions Comparators Outcomes Individuals:  With anal fistula(s) Interventions of interest are:  Placement of anal fistula plug Comparators of interest are:  Fistulotomy/fistulectomy  Endorectal/anal sliding flaps  Seton drains  Fibrin glue Relevant outcomes include:  Symptoms  Change in disease status  Morbid events  Functional out...

application of archie equation in carbonate reservoirs is not easy due to high dependence of its parameters on carbonate characteristics. carbonates are very heterogeneous in nature and hydrocarbon reserve estimation in these reservoirs of mostly oil-wet and intermediate-wet is highly influenced by the input values of saturation exponent. to our knowledge, non representative oils have been used...

This study evaluated the sealing ability of apical plugs made of white and gray MTA-Angelus and white Portland cement placed via the root canal and having different thicknesses (2, 5 and 7 mm). Ninety extracted human single-rooted teeth were instrumented using a size 40 K-file to standardize the foraminal opening by the stepback technique. The teeth were assigned to 3 groups (n=30), according t...

In the nematode Caenorhabditis elegans, a single gene (plg-1) encodes the dominant protein found in mating plugs - a means of inhibiting multiple matings. Naturally occurring loss of plg-1 function results in males that fail to deposit mating plugs - a manifestation of relaxed sexual selection since the evolution of self-fertilization in this species.

Sir, WethankDrsClark andLaskin for their interest in our recentlypublished systematic review of the effects of antiphospholipid antibodies on cultured placental cells in vitro.We agreewithmany of the authors’ comments and their suggestions for future investigations. However, in suggesting that trophoblast plugs prevent antiphospholipid antibodies accessing the placenta in early gestation, we be...

We developed a microfluidic platform for splitting well-mixed, femtoliter-volume droplets from larger water-in-oil plugs, where the sizes of the daughter droplets were not limited by channel width. These droplets were separated from mother plugs at a microfabricated T-junction, which enabled the study of how increased confinement affected enzyme kinetics in droplets 4-10 microm in diameter. Ini...