Excess dietary salt induces a cytochrome P450 arachidonic acid epoxygenase isoform in rat kidneys (Capdevila, J. H., S. Wei, J. Yang, A. Karara, H. R. Jacobson, J. R. Falck, F. P. Guengerich, and R. N. Dubois. 1992. J. Biol. Chem. 267:21720-21726). Treatment of rats on a high salt diet with the epoxygenase inhibitor, clotrimazole, produces significant increases in mean arterial blood pressure (...

The first phase-transfer catalyzed cyclopropanation reaction of chalcones using bromomalonates as the nucleophiles in a Michael Initiated Ring Closing reaction (MIRC) was developed. Key to success was the use of a free OH-containing cinchona alkaloid ammonium salt catalyst and carefully optimized liquid/liquid reaction conditions. The reaction performed well for electron neutral and electron de...

Nano dithiocarbamate (DTC) complex have been prepared by reaction between dithiocarbamate and metal salt under ultrasound irradiation. Reaction conditions such as the ligand DTC and phennantroline concentration, aging time and the ultrasonic device power show important roles in the size, morphology and growth process of the final products. The dithiocarbamate complex nanoparticles have been pre...

Etching egg shells with naturally acidic solutions is a traditional method of Easter eggs decorating. This technique, using only substances that are legally classified as food, easy to proceed and makes it possible demonstrate some basic chemical principles (such reaction between acid salt; the influence time temperature on course reaction).

True values of Michaelis constants of the NADP+-specific isocitrate dehydrogenase from Halobacterium salinarium were not very different from those of the apparent constants reported by Aitken et al. (1970). The true constants were affected by salt in a similar manner to that of the apparent constants obtained with NADP+ at fixed concentrations of 1."0.2mM and threo-Ds-(+)-isocitrate at fixed co...

Kinetic studies have been performed with crystalline dogfish liver glutamate dehydrogenase with the diphosphopyridine nucleotides as cofactors. The kinetic constants for the various substrates have been determined. In its sensitivity to guanosine S-triphosphate, adenosine S&phosphate, and excess reduced diphosphopyridine nucleotide the enzyme is similar to that derived from other vertebrates. T...

Kinetic studies have been performed with crystalline dogfish liver glutamate dehydrogenase with the diphosphopyridine nucleotides as cofactors. The kinetic constants for the various substrates have been determined. In its sensitivity to guanosine S-triphosphate, adenosine S&phosphate, and excess reduced diphosphopyridine nucleotide the enzyme is similar to that derived from other vertebrates. T...

The reaction of the hydroxyl radical with chloride on the surface of sea salt aerosol producing gas phase Cl2 and particulate OH and its implications for the chemistry of the marine boundary layer under coastal, remote, and very remote conditions have been investigated with a numerical model. This reaction had been suggested by Laskin et al. (2003) to play a major role in the sulfur cycle in th...