The study was conducted to assess & compare the effect of pretreatment with intravenous Dexmedetomidine and Magnesium sulphate on characteristics SAB hyperbaric bupivacaine. 80 ASA grade I II patients (age: 18-60 years) scheduled for infraumblical surgery under spinal anesthesia were included randomly divided into group-D (dexmedetomidine 1μ gm/kg) group-M (magnesium sulfate 50 mg/kg). give...

A new lateral approach to blocking the sciatic nerve in the popliteal fossa is described. In a prospective study, 40 patients scheduled for foot surgery involving osteotomies were allocated randomly into one of two groups following induction of general anaesthesia: group PS (n = 21) received a lateral popliteal sciatic nerve block and group SC (n = 19) received subcutaneous infiltration of the ...

We studied whether delivering postoperative analgesia, using a patient-controlled epidural analgesia (PCEA) device was effective and safe in elderly patients. We enrolled 40 patients aged > 65 years (elderly group) and 40 patients aged 20-64 years (young group) scheduled for elective major abdominal surgery. PCEA infusion was started following completion of surgery. Mean (SD) fentanyl consumpti...

AIM Vitrectomies are performed either under general anesthesia (GA), local anesthesia (LA), or a combination of both. Postoperative pain is expected to be less in patients with LA because of prolonged action of the local anaesthetic. Pre-emptive analgesia is based on the idea that analgesia initiated before a nociceptive event will be more effective than analgesia commenced afterwards. The auth...

BACKGROUND AND AIMS Caudal epidural analgesia is commonly practised regional block technique in children undergoing infraumbilical surgeries but has a short duration of action after single shot local anaesthetic injection. The aim of this study was to compare ropivacaine 0.25% with dexmedetomidine and tramadol in caudal anaesthesia in paediatric infraumbilical surgeries. METHODS In a randomis...

Pain is one of the most distressing post-operative consequences of surgeries. Opioids have been the mainstay in providing pain relief. Morphine is the considered to be the “gold standard” amongst opioids as an analgesic. Nalbuphine, a synthetic opioid agonist/antagonist has analgesic potency almost equivalent to that of morphine on a milligram basis and fewer complications like respiratory depr...

PURPOSE Lumbar laminectomy is a commonly performed procedure in neurosurgical and orthopedic practice. Postoperative pain reliefhelps in early mobilization, initiation of physiotherapy, provides satisfaction to the patients and plays an important role in reducing the morbidity and mortality. This prospective study investigated the simple technique of instillation of wound with bupivacaine and l...

BACKGROUND Apha-2 agonists are combined with local anesthetics to extend the duration of regional anesthesia. We evaluated the effect of combining dexmedetomidine with levobupivacine with respect to duration of motor and sensory block and duration of analgesia. METHODS Sixty patients scheduled for elective forearm and hand surgery were divided into two equal groups in a randomized double blin...

BACKGROUND Opioid and local anesthetic infusion by an epidural catheter is widely used as a postoperative pain management method after major abdominal surgeries. There are several agents nowadays to provide sufficient analgesia. The agents which cause less side effects but better quality of analgesia are more valuable. We aimed to postoperatively compare the analgesic, hemodynamic and arrhythmo...

Background: Regional anesthesia avoids airway instrumentation, preserves conscious level and provide rapid recovery with significant postoperative analgesia. There has always been a search for adjuvants to the regional nerve block drugs that prolong duration of analgesia but lesser adverse effects. The ideal additive still continues, therefore in this study, we investigated effects addition dex...