Supercritical Carbon Dioxide (sCO2) cycles can achieve higher efficiency compared to steam-Rankine or Air-Brayton cycles, therefore they are promising for concentrated solar power applications. Although sCO2 show design efficiency, the off-design is highly sensitive ambient conditions, impacting block net-power and heat input. In present work a recompression cycle connected central-tower field ...

Cytochrome c oxidase (CIV) deficiency is one of the most common respiratory chain defects in patients presenting with mitochondrial encephalocardiomyopathies. CIV biogenesis is complicated by the dual genetic origin of its structural subunits, and assembly of a functional holoenzyme complex requires a large number of nucleus-encoded assembly factors. In general, the functions of these assembly ...

Central hypovolemia elicited by application of lower body negative pressure (LBNP) has been used extensively to simulate hemorrhage in human subjects. Traditional LBNP protocols incorporate progressive steps in pressure held for specific time intervals. The aim of this study was to assess the reproducibility of applying continuous LBNP at a constant rate until presyncope to replicate actual ble...

The heart is a muscle with high energy demands. Hence, most patients with mitochondrial disease produced by defects in the oxidative phosphorylation (OXPHOS) system are susceptible to cardiac involvement. The presentation of mitochondrial cardiomyopathy includes hypertrophic, dilated and left ventricular noncompaction, but the molecular mechanisms involved in cardiac impairment are unknown. One...

In this study, the techno-economic performance of supercritical carbon dioxide (sCO2) power cycles in concentrating solar plants based on particle technology is assessed. A simplified levelized cost electricity calculation was used to investigate effect cycle parameters, compare layouts and allow for comparing optimized sCO2 blocks with steam technology. Results showed that simple fewer compone...

Sweet wormwood (Artemisia annua L.) valorization is gaining importance due to the presence of health-promoting bioactive compound, artemisinin. Considering wide possible application artemisinin drug formulations, new, greener technologies in their production are welcome. In this study, was extracted from A. leaves using green extraction (ultrasound-assisted extraction, supercritical CO2 deep eu...

Interest in supercritical CO2 power cycles is constantly increasing, showing good efficiency, and promising competitive costs enhanced flexibility with respect to competing systems. Some project within the EU Horizon 2020 program have studied these systems aim demonstrate them large scale, following example of STEP US. This work part effort SOLARSCO2OL build a sCO2-CSP demo plant at MW scale. A...

Supercritical CO2 central-receivers must withstand high temperatures and pressures combined with cyclic operation, which makes the solar receiver susceptible to creep-fatigue failure. In this work, a analysis of sCO2 Inconel 740H tubular 2 MWe tower plant has been accomplished study influence tube size on field design. A 2D numerical model that accounts for thermal conduction in both radial cir...