PURPOSE Scrophularia variegata M. Beib. (Scrophulariaceae) is an Iranian medicinal plant which is used for various inflammatory disorders in traditional medicine. In this study we evaluated the anti-cancer and cytotoxic effects of the Scrophularia variegata (S. variegata) ethanolic extract on the human breast cancer cell line. METHODS The cytotoxicity effect of the extract on MCF-7 cells was ...

In China, Scrophularia ningpoensis Hemsl (Scrophulariaceae) has been cultivated for many years; however, the effects of drought on the content of secondary metabolites in Radix Scrophulariaceae are still unknown. The study investigated the medicinal components of S. ningpoensis including harpagoside, aucubin, catalpol, harpagide, and cinnamic acid in relation to drought stress. Three ecotypes o...

BACKGROUND Although community structure and species richness are known to respond to nitrogen fertilization dramatically, little is known about the mechanisms underlying specific species replacement and richness loss. In an experiment in semiarid temperate steppe of China, manipulative N addition with five treatments was conducted to evaluate the effect of N addition on the community structure ...