A 15-year-old girl presented for evaluation of short stature and delayed sexual maturation. Her weight and height were 91 lb. (41 .3 kg) and 58 in. (147.3 em), respectively. She had not yet begun menstruating and had had no development of secondary sexual characteristics. Moderate ocular hypertelorism was present. A brain CT scan was initially interpreted as showing an intrasellar and suprasell...

In humans, as in all mammalian males, Leydig cells are the main source of the androgenic hormone, testosterone, which is essential for male sexual differentiation, gamete production and maturation, and development of secondary sexual characteristics. In this chapter, the development, steroidogenic function, and regulation of human Leydig cells are summarized. Clinical aspects of androgen secret...

abstract background: pregnancy can be in conflict with sexual function which can be affected by physical and psychological changes during pregnancy. therefore, comparison of the effect of face‑to‑face education with group education on sexual function during pregnancy in couples was the purpose of this research. materials and methods: in this quasi‑experimental pre‑test post‑test study, 64 pregn...

The success of any type of sexual education programme depends on the knowledge and preparedness for practice by adolescents. A recent study has found that an ‘abstinence-only’ sexual education programme is effective in reducing sexual activity among adolescents. Knowledge of abstinence-only sexual education and preparedness for practice as an effective tool for promotion of sexual health among ...

Background: A genital outflow tract obstruction is an uncommon cause of primary amenorrhea. If ovulation occurs, menstrual bleeding is prevented. Patients typically present with abdominal/pelvic pain due to hematocolpos. Absence of significant hematocolpos could indicate a secondary source of primary amenorrhea and be challenging to the clinical diagnosis. Case: 17 year-old patient with primary...

Complete sex reversal of fish is accomplished routinely in aquaculture practices by exposing fish to exogenous sex steroids during gonadal differentiation. A variety of environmental chemicals are also active at sex steroid receptors and theoretically possess the potential to alter normal sexual differentiation in fish. However, in controlled environmental chemical exposures to date, only parti...

The success of any type of sexual education programme depends on the knowledge and preparedness for practice by adolescents. A recent study has found that an 'abstinence-only' sexual education programme is effective in reducing sexual activity among adolescents. Knowledge of abstinence-only sexual education and preparedness for practice as an effective tool for promotion of sexual health among ...

Sexual dimorphism in common disease is pervasive, including a dramatic male preponderance in autism spectrum disorders (ASDs). Potential genetic explanations include a liability threshold model requiring increased polymorphism risk in females, sex-limited X-chromosome contribution, gene-environment interaction driven by differences in hormonal milieu, risk influenced by genes sex-differentially...

True isochromosomes for Xp probably do not exist in a liveborn. We describe a rare case of complete Xp duplication and retention of the inactivation centre at Xq13. Cytogenetically, it is described as a nonmosaic 46,X,psu idic(X)(q13). Complete duplication of Xpter-->Xq13 was confirmed by banded analysis and FISH probes for X centromere, Xp21, XIST locus, and whole chromosome paints for X and Y...

abstract background: women’s sexual self‑esteem is one of the most important factors that affect women’s sexual satisfaction and their sexual anxiety. various aspects of sexual life are blended with the entire personality. determining the relationship between personality traits and self‑concept aspects such as sexual self‑esteem leads to better understanding of sexual behavior in people with di...