Objectives: The saliva was first analyzed for the presence of anti-A and anti-B hemagglutinins in 1928. However, it was not been utilized as evidence in criminal investigations because of insufficient techniques available at that time. Hence, the present study was designed to evaluate feasibility of ABO group in medicolegal cases by determining the efficacy and accuracy of ABO blood group deter...

Background: It seems that there are similar associated diseases in psoriasis and Lewis (b) negative phenotypes such as diabetesmellitus, cardiovascular events, and metabolic syndrome. Therefore, we decided to evaluate the frequency of Lewis henotypes in patients with chronic plaque type psoriasis. A limited number of studies have been previously conducted in this regard.Methods: Fifty patients ...

Lewis phenotypes using various types of specimen were compared with the Lewis phenotype predicted from Lewis and Secretor genotypes. This is the first logical step in explaining the association between the Lewis expression and Helicobacter pylori. We performed a study of the followings on 209 patients who underwent routine gastroscopy: erythrocyte and saliva Lewis phenotyping, gastric Lewis phe...

Article Type : Full Length Research Article There are variations in the distribution of secretors and non-secretors in relation to ABO blood group which influence disease susceptibility from one region to another. In Nigeria, there are no reports on the proportion of secretors and nonsecretors among the Yoruba people of Southwestern region. This study was carried out to determine the secretor s...

Rotaviruses are known to recognize human histo-blood group antigens (HBGAs) as a host ligand that is believed to play an important role in rotavirus host susceptibility and host range. In this study, paired fecal and saliva samples collected from children with viral gastroenteritis, as well as paired serum and saliva samples collected from the general population in south China were studied to e...

BACKGROUND The impact of ABO incompatibility on hematopoietic stem cell transplantation (HSCT) outcome is controversial. As ABH substances are expressed on tissues and secreted in body fluids, they could drive an immune response in minor ABO-incompatible HSCT. The aim of the study was to investigate the prognostic role of the recipients' ABH secretor status. STUDY DESIGN AND METHODS Patients ...

Determining ABH secretor phenotype and/or Lewis (Le) blood group status can be useful to the metabolically-oriented clinician. For example, differences in ABH secretor status drastically alter the carbohydrates present in body fluids and secretions; this can have profound influence on microbial attachment and persistence. Lewis typing is one genetic marker which might help identify subpopulatio...

Human milk oligosaccharides (HMOs), as an abundant and bioactive component of breast milk, work in many ways to promote the health of breast fed infants. The expression of HMOs has been shown to vary in accordance with Lewis blood type and secretor status, as women of different blood types differ in the expression of α1,2 fucosyltransferase (FUT2) and α1,3/4 fucosyltransferase (FUT3). In this s...

Human milk oligosaccharides (HMOs) contain numerous biomolecules. It is the third most abundant solid component of breast milk, after lactose and lipids, that plays an important role in infant growth development human life. Several studies have reported health benefits HMOs, which include modulation intestinal microbiota, anti-adhesive effect against pathogens, epithelial cell response, immune ...

It has long been established that various human body secretions like saliva, semen, gastric juice contain blood group antigens. The individuals whose body fluids other than blood contain blood group antigens are known as secretors whereas the rest are nonsecretors. The secretor status of an individual is a genetically controlled factor. The role of genetic factors in the pathogenesis of duodena...