Our previous study established protein gene product 9.5 (PGP 9.5), a ubiquitin C-terminal hydrolase, as a specific cytochemical marker of synovial lining cells (type B synoviocytes) in the horse joint. The present study aimed to detect PGP 9.5 in the synovial fluid and shows that PGP 9.5 is a valuable marker of osteoarthritis in the horse. Immunohistochemical staining confirmed rich and consist...

STUDY DESIGN Retrospective cohort study. OBJECTIVE Lumbar segmental instability is a key factor determining whether decompression alone or decompression and fusion surgery is required to treat lumbar spinal stenosis (LSS). Some recent reports have suggested that facet joint effusion is correlated with spinal segmental instability. The aim of this study is to report the effect of facet effusio...

INTRODUCTION: Hallux valgus (HV) is a common first metatarsophalangeal (MTP1) joint deformity characterized by lateral deviation of the large toe, medial deviation of the first metatarsal, and hallux pronation [1,2]. Progressive subluxation of the MTP1 joint is common and results in attenuation of the medial soft tissues and contracture of the lateral soft tissues. The flexors and sesamoid comp...

background: posttraumatic and/or postsurgical knee stiff ness is one of the orthopedic complications which is difficult to be treated and can affect individual’s life negatively. the aim of this study is to investigate the results of quadricepsplasty in patients with knee stiff ness resulted from femoral fracture. materials and methods: this is a cross-sectional study on all patients with femor...

STUDY DESIGN A retrospective study. PURPOSE To assess postoperative bone regrowth at surgical sites after lumbar decompression with >5 years of follow-up. Postoperative preservation of facet joints and segmental spinal instability following surgery were also evaluated. OVERVIEW OF LITERATURE Previous reports have documented bone regrowth after conventional laminectomy or laminotomy and seve...

The author has derived the closed-form dynamic equations for a planar musculoskeletal chain composed of generic number n rigid links connected by ideal revolute joints. Single-joint and multi-joint muscles have been modeled as linear force actuators that can span from one joint to all joints chain. shape size each individual link accounts different alignments among center mass link, centers rot...

Synovial macrophages are one of the resident cell types in synovial tissue and while they remain relatively quiescent in the healthy joint, they become activated in the inflamed joint and, along with infiltrating monocytes/macrophages, regulate secretion of pro-inflammatory cytokines and enzymes involved in driving the inflammatory response and joint destruction. Synovial macrophages are positi...

OBJECTIVES Inflammatory arthritides/synovitides such as psoriatic (PsA), reactive (ReA) and rheumatoid (RA) arthritis share numerous immunopathological features, but develop different patterns of joint involvement. To investigate whether distinctive cell apoptosis may play a role in this context, we have assessed synovial cell apoptosis in situ in PsA and ReA, and compared it with RA and 'non-i...

OBJECTIVE To investigate whether local removal of phagocytic synovial lining cells (SLCs) from the knee joint before onset of collagen type II arthritis has an effect on development of cartilage destruction. METHODS Phagocytic SLCs were selectively depleted by a single injection of clodronate laden liposomes in the knee joint seven days before induction of collagen type II arthritis (CIA). Cl...