Objective. To test a theoretical explanatory model of the relationship between depression symptom scores and seizure frequency in people with epilepsy. Methods. A community based sample of adults with active epilepsy provided information on depression symptom scores and seizure frequency at two time points, one year apart. Results. 1210 patients completed the initial questionnaire and 976 of th...

BACKGROUND Seizures are a common symptom in patients with low-grade glioma (LGG), negatively influencing quality of life, if uncontrolled. Besides antiepileptic drugs, antitumour treatment might contribute to a reduction in seizure frequency. The aim of this study was to determine the effect of temozolomide (TMZ) chemotherapy on seizure frequency, to identify factors associated with post-treatm...

Epileptic seizures are generally considered to result from excess and synchronized neural activity. Additionally, changes in amplitude and frequency are often seen in local field potential or electroencephalogram recordings during a seizure event. To investigate how seizures initiate, and how dynamical changes occur during seizure progression, we develop a neocortical network model based on a m...

OBJECTIVES To examine the degree and frequency of reductions in hippocampal volume in patients with temporal lobe epilepsy with and without a history of febrile seizures. METHODS In vivo measures of hippocampal volume were computed from three dimensional gradient echo (FLASH) images in 44 patients undergoing comprehensive evaluations for epilepsy surgery. Twenty one patients (48%) reported a ...

Results Among patients 43.396% had seizure, 26.086% developed confusion after seizure and 17.391% experienced psychotic symptoms. Longer duration and larger quantity of substance abuse leads to higher complications. Seizure episodes occurred between 11 to 92 hrs of last intake with a median of 30 hrs. The seizure frequency had strong correlation with daily doses (b-0.697) and frequency (r-0.527...

Objective: understand the psychological considerations of the relationship between the effect of seizures upon the patients’ perception of seizure control, depression, anxiety and quality of life (QoL). Methods: 151 adult patients with epilepsy diagnosed for over two years were interviewed and responded the 31-Item Quality of Life in Epilepsy (QOLIE-31), the Trait Form of the State/Trait Anxiet...

Electroconvulsive therapy (ECT) effect upon seizure cessation was studied in five male Wistar rats using a penicillin intracisternal injection model (which did not damage the cranial vault). Animals were observed both clinically and electrographically for seizure development. ECT was applied at varying times following onset of seizure, at varying parameters (frequency, pulsewidth, and duration)...

D ysfunction in the central nervous system of the neonate is often rst identi ed through seizures. The di culty in detecting clinical seizures, which involves the observation of physical manifestations characteristic to newborn seizure, has placed greater emphasis on the detection of newborn electroencephalographic (EEG) seizure. The high incidence of newborn seizure has resulted in considerabl...