Background: Despite introduction of modern antiepileptic drugs, 30% of epileptic patients are still drug resistant. Remarkable three-dimensional spatial structure of AdCA, yet the simplicity of the molecule, makes AdCA a promising lead compound. Methods: Sedative/motor impairment and 24-h mortality rate of AdCA were determined in mice. Impact of AdCA on (1) threshold and occurrence of clonic se...

  Background Seizures may occur in as many as 1% of children. The most urgent type of seizures is generalized tonic-clonic seizures (GTCS). N-terminal prohormone of brain natriuretic peptide (NT‐proBNP) has been considered as a promising biomarker in numerous acute illnesses. We aimed to evaluate usefulness of NT‐proBNP for diagnosis of g...

ObjectiveTo describe the epidemiology and health resource utilization for convulsive status epilepticus (SE) in emergency department (ED).MethodsRetrospective descriptive study Nationwide Emergency Department Sample (NEDS). Primary SE secondary (SE a case who visited ED other primary reason) were compared with non-SE seizures. Secondary is expected to have worse outcomes higher costs because of...

Febrile Seizures are seizures that appear during fever because it is caused by an intracranial process, as there infections of the respiratory tract, ears, and digestive tract. According to SIKI guidebook, several nursing actions performed integrated into dealing with hyperthermia classified observational, therapeutic, educational, collaborative actions. The purpose this study was determine mai...

Abstract Seizures in neonates should prompt rapid evaluation to verify the diagnosis, determine etiology, and initiate appropriate treatment. Neonatal seizure diagnosis requires EEG confirmation clinical observation alone is insufficient. Although most neonatal seizures are related acute brain injury, some present early-onset structural or metabolic/genetic epilepsy. Video-EEG monitoring, gold ...