Undesirable taste is one of several important formulation problems that are encountered with certain drugs. The problem of bitter and obnoxious taste of is a challenge to the pharmacist in the present scenario. Several oral pharmaceuticals and bulking agents have unpleasant, bitter-tasting components. The desire of improved palatability in these products has prompted the development of numerous...

Waterhyacinth is one of the fastest growing plants which disrupt the ecological balance. The plant inspite of its obnoxious nature, is a source of various pharmacologically active compounds. Sterols were isolated from the ethyl acetate extract of waterhyacinth and characterized to be a mixture of stigmasterol and β-sitosterol based on UV, IR, 1D and 2D NMR studies. Quantification of the isolate...

Extensive use of indwelling devices in modern medicine has revoked higher incidence of device associated infections and most of these devices provide an ideal surface for microbial attachment to form strong biofilms. These obnoxious biofilms are responsible for persistent infections, longer hospitalization and high mortality rate. Gene regulations in bacteria play a significant role in survival...

A single man aged 65 years was referred to the Department of Venereology in 1949 on account of extensive necrosis of the skull and gangrene of the right foot. The precipitating factor was an obnoxious smell, attributed to a blocked drain, which was reported by some of his neighbours to the local Sanitary Authority. Through the Medical Officer of Health, the patient was eventually compelled to a...

Geometric branch-and-bound methods are popular solution algorithms in deterministic global optimization to solve problems in small dimensions. The aim of this paper is to formulate a geometric branch-and-bound method for constrained global optimization problems which allows the use of arbitrary bounding operations. In particular, our main goal is to prove the convergence of the suggested method...

The network Security is the hottest topic in the current research scenario. The information security is really threatened by obnoxious users. With increasing vulnerabilities, caused by port scan attacks, replay attacks and predominantly IP Spoofing, targeting services, the network behavior is getting malevolent. But there is a lack of any clear threat model. The authors have endeavored to consi...

Amma Darko follows in the tracks of the two leading Ghanaian women writers, Efua Sutherland and Ama Ata Aidoo. However, as a writer, Darko differs in her approach to social, political and cultural issues. Her first three novels, Beyond the Horizon (1995), The Housemaid (1998) and Faceless (2003), all present and contest the culture of patriarchy. In her works, women are victims of rape, battery...

Efficient algorithms for solving the center problems in weighted cactus networks are presented. In particular, we have proposed the following algorithms for the weighted cactus networks of size n: an O(n log n) time algorithm to solve the 1center problem, an O(n log 3n) time algorithm to solve the weighted continuous 2-center problem. We have also provided improved solutions to the general p-ce...

" Congenital internal bending back of the sternum and ribs as the cause of difficulty in breathing. " My father showed me a boy seven years old at the house of a nobleQaan of Andlau, whose ensiform cartilage and other parts of the chest bone, together with the ribs, was bent back towards the internal parts, 8o that a great hollow appeared there. The diaphragm, he pointed out, deemed to contract...

This paper proposes a model for obnoxious waste location-routing problem (LRP) considering various types of wastes and several treatment technologies. The investigated distribution network includes three echelons of generation nodes, treatment and disposal facilities. A multi-objective LRP model is developed with three objective functions minimizing the treatment and disposal facility undesirab...