Most hinnies (female donkey×male horse) and mules (female horse×male donkey) are sterile with few reports of equine fertile hybrids. The main cause of this sterility is thought to be a meiotic block to spermatogenesis and oogenesis. This study compared the developmental features of the testes and a histological analyses of spermatogenesis in a male hinny with those of a normal, fertile stallion...

BACKGROUND Calcifying nanoparticles (NPs) have been proven to be associated with a variety of pathological calcification and previously detected in semen samples from patients with testicular microlithiasis (TM). The present study was designed to test the hypothesis if human-derived NPs could invade the seminiferous tubules and induce TM phenotype. METHODS The animals were divided into three ...

background: in traditional medicine zingiber officinale used to regulate female menstural cycle and treat male infertility. recent studies have suggested the possible role of ginger extract in improving the testicular damage of busulfan. objective: the aim of this study was to evaluate the effects of zingiber officinale on the sperm parameters, testosterone level and the volume of the testes an...

Article history: Received on: 14/12/2014 Revised on: 08/01/2015 Accepted on: 22/01/2015 Available online: 27/02/2015 Testis is the tissue with immune privilege which is maintained by blood-testis barrier to protect autoimmunogenic components of testis. IgG have binding affinity for CD16, CD32 and CD64 receptors present on various immune cells. Present study was conducted to investigate the IgG ...

Reproductive health problem is more common nowadays and various causes like nutritional defect, socio-economic problems, life style changes are reason for that, among those reason, one important factor is environmental factor. In this study, the pesticide, Lindane is used to induce reproductive toxicity and the levels of male reproductive hormone, antioxidant and histopathology of rat testis wa...

The functional and morphological evidence for the blood-testis barrier is discussed, together with evidence for the various processes (simple diffusion and facilitated diffusion) by which various substances enter the seminiferous tubule. Data are presented to show that methylmethane-sulfonate (MMS) and dimethylnitrosamine (DMNA) both enter the seminiferous tubules rapidly, although from the pub...

Research on spermatogonia is hampered by complex architecture of the seminiferous tubule, poor viability of testicular tissue ex vivo and lack of physiologically relevant long-term culture systems. Therefore there is a need for an in vitro model that would enable long term survival and propagation of spermatogonia. We aimed at the most simplified approach to enable all different cell types with...

OBJECTIVE Concerns are growing about the decrease in male reproductive health. Caffeine is one of the popular nutrients that has been implicated as a risk factor for infertility. In the present study, we examined whether in utero and lactational exposure to caffeine affects the reproductive function of the offspring of rats. METHODS Pregnant rats received caffeine via drinking water during ge...