OBJECTIVE We evaluated a workplace preventive program's effectiveness, which emphasized skin and respiratory protection, workplace cleanliness, and beryllium migration control in lowering beryllium sensitization. METHODS We compared sensitization prevalence and incidence rates for workers hired before and after the program using available cross sectional and longitudinal surveillance data. ...

objective: asthma is an airway complex disease defined by reversible airway narrowing and obstruction, chronic airway inflammation, airway hyperresponsiveness, and tissue remodeling. the purpose of this study was to determine the effect of brassica napus l. (b. napus) on airway pathologic changes in a rat model of asthma. materials and methods: twenty-four rats were divided into 4 groups: contr...

background: cuminum cyminum fruit essential oil (feo) dose-dependently can attenuate the expression of morphine tolerance and dependence in morphine-dependent mice. objective: in this study, the effects of cuminum cyminum feo on acquisition and expression of morphine-induced conditioned place preference (cpp) in morphine-sensitized mice were studied. methods: repeated subcutaneous (s.c.) admini...

introduction: the diagnostic work-up of allergic rhinitis (ar) is first and foremost based on the combination of clinical history data and results of skin prick tests (spt). other tests, including specific ige measurement, nasal challenge, and, as a third option, component resolved diagnosis or basophil activation test, may be useful when the diagnosis is difficult because of polysensitization ...

Sensitization refers to an increase in sensitivity to the effects of a drug and is believed to play a role in the etiology of substance use disorders. Cross-sensitization has been observed between drugs from different pharmacological classes and may play a role in the escalation of drug use in polydrug-abusing populations. The purpose of this study was to examine cross-sensitization between opi...

Flying insects have developed a remarkably sensitive olfactory system to detect faint and turbulent odor traces. This ability is linked to the olfactory receptors class of odorant receptors (ORs), occurring exclusively in winged insects. ORs form heteromeric complexes of an odorant specific receptor protein (OrX) and a highly conserved co-receptor protein (Orco). The ORs form ligand gated ion c...

Lung cancer is managed using conventional therapies, including chemotherapy, radiation therapy, or a combination of both. Each these therapies has its own limitations, such as the indiscriminate killing normal well cells, solubility chemotherapeutic drugs, rapid clearance drugs from circulation before reaching tumor site, resistance cells to radiation, and over-sensitization radiation. Other tr...

Background More knowledge about sensitization patterns in early infancy, including impact of molecular allergology, is needed to help predict future allergy development more accurately. Objective We aimed determine the prevalence and allergic at 3 months age, explore possible associated factors. Methods From Scandinavian antenatally recruited PreventADALL mother–child cohort, we included 1110 3...

OBJECTIVE This study clarified sensitization patterns to house dust mite (HDM) and Japanese cedar pollen (JCP) in Japanese lower-grade schoolchildren. We also explored factors associated with allergic sensitization. METHODS This cross-sectional study used a database from the Study on Respiratory Disease and Automobile Exhaust (SORA), a Japanese health study project. The subjects comprised 8,8...

Primary allergic sensitization--IgE formation after Ag exposure--is fundamental in the development of allergic respiratory disease. With the rising prevalence of asthma and allergic rhinitis, improved understanding of the determining factors for allergic sensitization is needed. Human epidemiologic studies suggest high-dose allergen exposure may paradoxically protect against sensitization. Pros...