Background: Sepsis is a life-threatening condition that arises when the body's response to infection causes injury its own tissues and organs.
 Materials methods: This was cross sectional study conducted at Baraah pediatric center, Khartoum, Sudan during period from May 2022 August 2022, measure protein C level in Sudanese children infants with Sepsis. 50 patients were selected as case gro...

Objective To improve susceptibility profiles of nosocomial bacteria, identifying the difference between infectious complications in patients undergoing endoscopic flexible ureterolithotomy (fURS) with negative urine culture (UC) that received extended antibiotic prophylaxis (EP) compared standard (SP). Methodology This is a retrospective, observational, analytical cohort study, comparing fURS U...

Objective: An irreversible process begins when a systemic infection causes sepsis. Therefore, rapid identification of the agent bacteria in sepsis and its antibiotic resistance is crucially important. In this study, it was aimed to investigate efficiency genotype test.
 Methods: Blood culture bottles sent laboratory were examined with an automatic blood system (BACTEC, BD, USA). Growing id...

OBJECTIVES To determine the occurrence rate, outcomes, and the characteristics of severe sepsis in surgical intensive care units in multiple medical centers within China and to assess the cost and resource use of severe sepsis in China. DESIGN AND SETTING Prospective, observational study of surgical intensive care unit patients at ten university hospitals in six provinces in China. PATIENTS...

Susceptibility to bacterial infections after a primary immune stimulation differs drastically depending on the presensitization of the innate immune system. To determine the conditions that either induce protection or enhanced susceptibility to infection with Salmonella enterica serovar Typhimurium, we pretreated mice either with tumor necrosis factor (TNF), whole killed bacteria, or sublethal ...

Vibrio vulnificus is an opportunistic pathogen of humans that has the capability of causing rare, yet devastating disease. The bacteria are naturally present in estuarine environments and frequently contaminate seafoods. Within days of consuming uncooked, contaminated seafood, predisposed individuals can succumb to sepsis. Additionally, in otherwise healthy people, V. vulnificus causes wound in...

One hundred patients undergoing major surgical operations in a provincial group hospital were studied bacteriologically daily to determine any relation between nasal carriage of staphylococci and post-operative staphylococcal wound sepsis.Sixty-four patients were either carriers on admission and throughout their stay, or their noses became colonized at some time by ward strains. Six cases of st...

Sepsis, caused by uncontrollable infection and inflammatory response, leads to more than 30 million infected patients results in high morbidity worldwide every year. Currently, no efficient approaches have been developed for sepsis therapy due antimicrobial resistance storm. Here, we report macrophages loaded with aggregated carbon dots (ACDs) the lysosome, termed MCDs, treat immunosuppressive ...

A common feature of severe sepsis is vascular inflammation and damage to the endothelium. Because platelets can be directly activated by bacteria and endotoxin, these cells may play an important role in determining the outcome of sepsis. For example, inhibiting platelet interactions with the endothelium has been shown to attenuate endothelial cell damage and improve survival during sepsis. Alth...

Aim and objective: The management of patients with sepsis and septic shock requires an integrated approach of accurate diagnosis along with rapid initiation of appropriate antimicrobial therapy. Here we present a retrospective analysis of a new therapy opted and outcome of the patients suffering from gram negative bacterial sepsis. Materials and methods: A retrospective study was conducted to e...