نتایج جستجو برای: serous
تعداد نتایج: 11093 فیلتر نتایج به سال:
INTRODUCTION We present a unique case of a patient with bilateral, multifocal central serous retinopathy in a patient with alcoholic liver disease. CASE PRESENTATION A 58-year-old Caucasian man with alcoholic liver disease, liver cirrhosis and ascites presented to the eye clinic. The ophthalmoscopic examination of both eyes revealed a symmetrical pattern of variably sized, slightly yellowish,...
OBJECTIVE Serous carcinoma and clear cell carcinomas account for 10% and 3% of endometrial cancers but are responsible for 39% and 8% of cancer deaths, respectively. In this study, we aimed to compare serous carcinoma and clear cell carcinoma regarding the surgico-pathologic and clinical characteristics, and survival, and to detect factors that affected recurrence and survival. MATERIALS AND ...
Serous uterine cancer is not a feature of any known hereditary cancer syndrome. This study evaluated familial risk of cancers for patients with serous uterine carcinoma, focusing on Lynch syndrome malignancies. Fifty serous or mixed serous endometrial carcinoma cases were prospectively enrolled. Pedigrees were developed for 29 probands and tumors were assessed for DNA mismatch repair (MMR) abno...
Abstract Objective Identifying potentially modifiable risk factors for ovarian cancer is essential prevention because this predominantly detected at a late stage. Here, we estimated the relations of general adiposity and measures reflecting body fat distribution to epithelial cancer. Methods We ascertained 683 cancers (343 high-grade serous, 141 non-high grade serous) among 145,575 women, aged ...
BACKGROUND Oxidative damage and DNA repair dysfunction are associated with carcinogenesis. 8-OHdG is one of the major oxidative DNA adducts. Present work aims to investigate whether the expression of 8-OHdG and its key repair gene hOGG1 play distinctive role in two types of serous ovarian cancer. MATERIALS AND METHODS 8-OHdG level in DNA from tumor and matched tumor-adjacent normal tissue in ...
Cystic tumors of the pancreas are rare neoplasms. They are more frequently identified given the improvements in imaging techniques. Serous cystadenomas are the most common among cystic neoplasms of the pancreas. In this case report we present a patient who was incidentally found to have a cystic mass in the pancreas during an abdominal imaging done for unrelated reasons and was diagnosed as ser...
Central serous chorioretinopathy is a common acquired maculopathy. Multiple studies showed that photodynamic therapy is useful treatment for acute and chronic central serous chorioretinopathy. The exact mechanism of photodynamic therapy in treating central serous chorioretinopathy is not clear, but it is thought to be caused by short-term choriocapillaris hypoperfusion and long-term choroidal v...
Background & Aims: ovarian cancer is the 4th leading cause of cancer-related death in women. In order to reduce its mortality and morbidity, identification and evaluation of specific diagnostic biomarkers are necessary. Given the importance of the GADD45A role in cell survival and death, its expression changes were investigated in benign, borderline and malignant ovarian serous tumors in the pr...
PURPOSE To understand the pathophysiology of central serous chorioretinopathy or bullous retinal detachment in patients under systemic corticosteroid treatment. Little is understood about the mechanism of the development of serous retinal detachment. METHODS Three patients who had developed central serous chorioretinopathy or bullous retinal detachment during systemic corticosteroid administr...
BACKGROUND Primary high-grade serous peritoneal carcinoma (PPSC) is a rare malignancy with an ambiguous pathogenesis. CASE REPORT We report on a 51-year-old woman presenting with a routine smear test cytology suspicious of adenocarcinoma. She underwent hysteroscopy, laparsocopy with multiple biopsies and bilateral salpingoophorectomy. She was diagnosed with a serous tubal intraepithelial carc...
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