نتایج جستجو برای: serous tumors

تعداد نتایج: 187057  

2011
Michael P. Stany Vinod Vathipadiekal Laurent Ozbun Rebecca L. Stone Samuel C. Mok Hui Xue Takashi Kagami Yuwei Wang Jessica N. McAlpine David Bowtell Peter W. Gout Dianne M. Miller C. Blake Gilks David G. Huntsman Susan L. Ellard Yu-Zhuo Wang Pablo Vivas-Mejia Gabriel Lopez-Berestein Anil K. Sood Michael J. Birrer

Clear cell ovarian cancer is an epithelial ovarian cancer histotype that is less responsive to chemotherapy and carries poorer prognosis than serous and endometrioid histotypes. Despite this, patients with these tumors are treated in a similar fashion as all other ovarian cancers. Previous genomic analysis has suggested that clear cell cancers represent a unique tumor subtype. Here we generated...

2017
Jun Zhang Jun-Chao Wang Yue-Hong Li Rui-Xue Wang Xiao-Mei Fan

BACKGROUND Ovarian serous adenocarcinoma can be divided into low- and high-grade tumors, which exhibit substantial differences in pathogenesis, clinicopathology, and prognosis. This study aimed to investigate the differences in the PH domain leucine-rich repeat protein phosphatase (PHLPP), forkhead homeobox type O 3a (FoxO3a), and RAD51 protein expressions, and their associations with prognosis...

Journal: :Ginekologia polska 2015
Sevil Sayhan Gulden Diniz Tugba Karadeniz Duygu Ayaz Dudu Solakoglu Kahraman Mehmet Gokcu Hulya Tosun Yildirim

BACKGROUND Previous studies have demonstrated that Caveolin-1 (Cav-1) can ambiguously behave as tumor suppressor or tumor promoter in different neoplasms, depending on cancer type. Some findings have also revealed that cell proliferation, migration and invasion were attenuated by the knockdown of Caveolin-1 expressions. However, the functional and prognostic significance of Caveolin-1 in most t...

2013
Leszek Gottwald Marian Danilewicz Jacek Suzin Malgorzata Wagrowska-Danilewicz Michal Spych Wieslaw Tylinski Katarzyna Topczewska-Tylinska Janusz Piekarski Sylwia Kazmierczak-Lukaszewicz Aleksandra Cialkowska-Rysz

INTRODUCTION There is a need to assess the value of the novel potentially useful biomarkers in ovarian tumors. The aim of study was to assess the value of sAgNOR analysis in ovarian serous epithelial tumors. MATERIAL AND METHODS The analysis was performed in ovaries from 113 patients treated operatively due to serous ovarian tumors (30 adenomas, 14 borderline tumors and 69 cancers). After sil...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1996
B J Simpson A D Ramage M J Hulme D J Burns D Katsaros S P Langdon W R Miller

The regulatory subunits of protein kinase A, or cyclic AMP-binding proteins, were measured in a series of 107 human ovarian tumors (89 malignant, 7 borderline, and 11 benign tumors) and related to tumor clinicopathological features and patient survival. Total cyclic AMP-binding protein levels were not significantly different between malignant tumors and either borderline or benign tumors. Howev...

Journal: :Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 2005
Susumu Okada Yoshiharu Ohaki Kohei Inoue Takashi Kawamura Toshihiko Hayashi Tomoyasu Kato Tatsuo Kumazaki

Mucinous cystic ovarian tumors sometimes contain calcifications, but the frequency and significance of such calcifications in diagnostic radiology are not well understood. We therefore retrospectively investigated the radiological and histopathological evidence of calcifications in 44 cases of ovarian mucinous cystic tumors (22 benign, 13 borderline, and 9 malignant) and 21 cases of ovarian ser...

2015
Gouthaman Shanmugasundaram Elilnambi Sundaramoorthy Suresh Sudalaiandi Satish Srinivas Kondaveeti Thanka Johnson Rajendiran Swaminathan Anita Ramesh

Surface epithelial stromal tumors account for approximately 60% of all ovarian tumors and approximately 90% of all ovarian malignancies. Sex cord stromal tumors account for 7% of all malignant ovarian tumors. Germ cell tumors make up only 3-7% of malignant ovarian tumors. A combination of serous carcinoma of the ovary and choriocarcinoma is rare. Until today such combination has been documented...

Journal: :Clinical chemistry 1982
J J Zakowski D E Bruns

We describe a column-chromatographic method for measuring amylase activity in cyst fluids of serous ovarian tumors. Using this technique, we confirm and extend the previous report of an "acidic" amylase in serous ovarian tumor cyst fluids. This form of the enzyme was eluted from DEAE-Sephadex mini-columns with a high-salt buffer. It accounted for 45 to 100% of the amylase in 13 cyst fluids. Thi...

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