AIM To study bone turnover following renal transplantation using a panel of biochemical markers and to correlate the results with both areal and volumetric bone mineral density (BMD). PATIENTS A total of 31 patients aged 18.1 years were transplanted 5.4 years before this study. Control patients (n = 31) were age and gender matched. METHODS In addition to measurement of biochemical markers, ...

Analyzing biochemical turnover markers will be helpful to predict the bone health status of individuals. The present study aimed at studying the two essential enzymes involved in bone turnover process viz., serum acid phosphatase and serum alkaline phosphatase which are considered as bone resorption and bone formation marker respectively among urban women aged 35 to 74 years. The findings well ...

AIM To investigate the diagnostic accuracy of potent serum biochemical fibrosis markers in children with chronic hepatitis B evaluated by receiver operating characteristics (ROC) analysis. METHODS We determined the serum level of apolipoprotein A-I (APO A-I), haptoglobin (HPT) and a-2 macroglobulin (A2M) with an automatic nephelometer in 63 children (age range 4-17 years, mean 10 years) with ...

Testicular cancer has become a model for a curable neoplasm, where biochemical markers play a critical role. Serum tumor markers are integral in patient management and contributes to the diagnosis, staging, and risk assessment, as well as evaluation of response to therapy and detection of relapse. We review their biochemistry, biology, and clinical use in the setting of localized and metastatic...

Objective. To assess serum level of Dickkopf-1 in postmenopausal females and its correlation with bone mineral density and serum biochemical markers. Methods. Bone densitometry, serum Dickkopf-1, calcium, phosphorus, and alkaline phosphatase were done in sixty postmenopausal females. Patients were divided according to T score into osteoporosis (group I), osteopenia (group II), and normal bone m...

OBJECTIVE The presence of YKL-40 (human cartilage glycoprotein 39) in synovium, cartilage and synovial fluid (SF) from knee joints of patients with rheumatoid arthritis and osteoarthritis (OA) were related to histopathological changes in synovium and cartilage and to serum YKL-40 and other biochemical markers. METHODS The localization of YKL-40 in synovium and cartilage was determined by immu...

Introduction and Aim: The number of patients suffering from end stage renal disease (ESRD) requiring dialysis has increased worldwide. Mineral bone disorders (MBD) commonly occur in ESRD patients. MBD is classified into high turnover low disease. Biochemical parameters play a key role classifying MBD. Data on adynamic (ABD) hemodialysis (HD) sparse. aim to study the prevalence biochemical profi...

The awareness of osteoporosis has grown worldwide in recent years. This silently progressing metabolic bone disease is widely prevalent in India, and osteoporotic fractures are a common cause of morbidity and mortality in Indian women. Rapid bone loss occurs in postmenopausal women due to hormonal factors which lead to increased risk of fractures. Biochemical markers of bone metabolism are used...

Background: Osteoporosis is one of the prevalent diseases post-Menopausal women. Hence to evaluate severity osteoporosis serum calcium, ALP and urinary hydroxyproline used as bone resorption marker.Method: 30 post-menopausal women with were compared healthy pre-menopausal 25-40 years Random Blood sample collected from venipuncture centrifuged get serum. Fasting Urine was 1.2 drops 6 N HCI added...