Triglyceride synthesis by hepatocytes is currently thought to be the rate-limiting step for lipoprotein formation. In order to determine whether triglyceride and cholesteryl ester syntheses in hepatocytes are sensitive to physiological fluctuations of serum fatty acids, the fatty acid dependence of these pathways was examined. Uptake of various fatty acids and incorporation into triglyceride an...

The authors assessed the association between serum phospholipid fatty acids as biomarkers of fatty acid intake and breast cancer risk among women in the E3N Study (1989-2002), the French component of the European Prospective Investigation into Cancer and Nutrition. During an average of 7 years of follow-up, 363 cases of incident invasive breast cancer were documented among 19,934 women who, at ...

Changes in fatty acid patterns of lipids in serum and erythrocytes in duced by dietary fats and in vitro incorporation of fatty acids into ery throcyte membranes were investigated with pigs. On feeding various diets, it was found that fatty acid composition of serum and erythrocytes could be modified and altered toward the fatty acid pattern of the diet . In vitro, the incorporation of labeled ...

The authors assessed the association between serum phospholipid fatty acids as biomarkers of fatty acid intake and breast cancer risk among women in the E3N Study (1989–2002), the French component of the European Prospective Investigation into Cancer and Nutrition. During an average of 7 years of follow-up, 363 cases of incident invasive breast cancer were documented among 19,934 women who, at ...

We report unusually high concentrations of free fatty acids and glycerol in sera of patients with adult-onset diabetes, and the accompanying alterations in creatine kinase isoenzyme MM patterns associated with such patients. The serum samples with increased free fatty acids also showed increased electrophoretic movement of the MM isoenzyme on cellulose acetate membranes. Fatty acid concentratio...

PURPOSE OF REVIEW Fish oils rich in n-3 fatty acids reduce serum triglyceride levels. This well known effect has been shown to be caused by decreased very low-density lipoprotein triglyceride secretion rates in kinetic studies in humans. Animal studies have explored the biochemical mechanisms underlying this effect. Triglyceride synthesis could be reduced by n-3 fatty acids in three general way...

Several investigations have reported an increase, in stored serum, in apparent thyroxine (T4) concentration measured by competitive binding radioassay (CPBR) with thyroxine-binding globulin (TBG) as the binding reagent [l-7]. Watson and Lees [4] attributed this increase to the production of a “mimic T4” during storage. Recently, we [6] and Rootwelt [7], working independently, discovered that th...

There is some evidence that alpha-linolenic acid might be positively related to prostate cancer risk. Associations between serum fatty acid composition as well as fatty acid intakes and prostate cancer risk were examined in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. The cohort included 29,133 male smokers aged 50-69 years. During 5-8 years of follow-up, 246 prostate cancer cas...

We have developed a quick, reliable method for compositional analysis of the C14 to C20 fatty acids of cholesteryl esters, based on the use of a double extraction-solvent system and whisker-walled capillary columns with a new polar phase. Fatty acids of phosphatidylcholine, after separation by thin-layer chromatography, were determined on the same column. Our normal values are in good agreement...

changes in the fatty acid content, during frozen storage at -24°c of caspian kutum (rutilus frisii kutum), golden grey mullet (liza aurata), common carp (caprinus carpio), pike perch (sander lucioperca) and common kilka (clupeonella cultiventris caspia), caught from south caspian sea were studied in the present work. changes in saturated fatty acids (sfas), monounsaturated fatty acids (mufas), ...