Feline Infectious Peritonitis (FIP) is a fatal disease caused by feline coronaviruses. The causative agent Virus, mutation of Enteric Coronavirus. Corona Virus very common in the cat population. In infected cats, development FIP depends on cat's immune response. more young and old cats because animals have weaker system. acute phase response complex systemic reaction that occurs as to or chroni...

introduction: serum c-reactive protein (crp) is believed to be increased in metastatic urothelial cancer of the bladder. however, the changes depend on the stage and grade of the upper tract urothelial carcinoma (utuc). this study aimed to compare low-range and high-range serum crp and haptoglobin in new cases of utuc. materials and methods: blood was collected from newly diagnosed patients wit...

The total concentrations of alpha(2) globulin and two of its components, haptoglobin and caeruloplasmin, have been determined in the sera from 78 patients with primary malignant diseases of lympho-reticular tissue (reticuloses). The total alpha(2) globulin fraction was significantly raised only in Hodgkin's disease. The serum haptoglobin was also significantly increased in Hodgkin's disease and...

The serum concentration of 19 serum proteins was determined by electrophoresis in 42 patients with Crohn's disease and 36 patients with ulcerative colitis. The results were compared with 78 healthy persons as matched controls. Distinctive, but similar, changes were present in the two diseases. An increased serum concentration of orosomucoid, alpha(1)-antitrypsin, easily precipitable glycoprotei...

BACKGROUND Systemic inflammation is observed in horses with heaves and could also be present in horses with a lesser degree of pulmonary inflammation. HYPOTHESIS/OBJECTIVES It was hypothesized that racehorses with inflammatory airway disease (IAD) have increased concentration of circulating acute phase proteins. The objective of this study was to compare serum acute phase proteins of racehors...

Identication of early hepatocellular carcinoma (HCC) in patients with chronic liver diseases (CLD) is an important clinical task. Previous studies have shown that patterns of alpha-2,6-sialylation and alpha-1,6-fucosylation change in liver cancer, leading to aberrant glycosylations on some serum proteins. In this study, we purified alpha-2,6-sialylated and alpha1,6-fucosylated serum glycoprotei...

BACKGROUND Haptoglobin (H) is a glycoprotein that regulates the immune response. Serum haptoglobin levels are significantly higher in patients with advanced epithelial ovarian cancer (EOC) with poor survival. Different isoforms of haptoglobin have been found in the serum of patients with EOC. We studied the genetic susceptibility and outcome of patients with EOC correlated to H phenotypes. MA...

Gallbladder cancer is the most common malignant tumor of the biliary tract. Early diagnosis of gallbladder cancer is difficult because of the latent onset and lack of good biomarkers. To identify new biomarkers that improve the early diagnosis and/or serve as possible therapeutic targets in gallbladder cancer is essential. In the present study, serum proteins were separated by two-dimensional g...

The purpose of this study was to assess the diagnostic value of fibrinogen, haptoglobin, and serum amyloid A determination in the monitoring of the treatment of limb diseases in dairy cows. Fourteen lame cows were examined, while 10 clinically healthy cows constituted the control group. Blood samples from the ill animals were collected on three occasions: (1) upon arrival at the clinic, (2) bet...

X-linked muscular dystrophy is caused by primary abnormalities in the Dmd gene and is characterized by the almost complete loss of the membrane cytoskeletal protein dystrophin, which triggers sarcolemmal instability, abnormal calcium homeostasis, increased proteolysis and impaired excitation‑contraction coupling. In addition to progressive necrosis, crucial secondary pathologies are represented...